CXCL5 蛋白
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- 抗原 See all CXCL5 蛋白
- CXCL5 (Chemokine (C-X-C Motif) Ligand 5 (CXCL5))
- 生物活性
- Active
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宿主
- 小鼠
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资源
- 大肠杆菌(E. Coli)
- 序列
- APSSVIAATE LRCVCLTVTP KINPKLIANL EVIPAGPQCP TVEVIAKLKN QKEVCLDPEA PVIKKIIIQK ILGSDKKKAK RNALAVERTA SV
- 产品特性
- Fully biologically active when compared to standard. The ED50 determined by a chemotaxis bioassay using human peripheral blood neutrophils is less than 100 ng/ml, corresponding to a specific activity of >, 1.0 × 104 IU/mg.
- 纯度
- > 97 % by SDS-PAGE and HPLC analyses.
- 内毒素水平
- Level Less than 1EU/µg of rMuLIX/CXCL5 as determined by LAL method
- Top Product
- Discover our top product CXCL5 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at < -20 °C. Further dilutions should be made in appropriate buffered solutions.
- 储存条件
- 4 °C
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- 抗原
- CXCL5 (Chemokine (C-X-C Motif) Ligand 5 (CXCL5))
- 别名
- LIX/CXCL5 (CXCL5 产品)
- 背景
- The mouse homolog of ENA-78 is called LIX. ENA-78/LIX is a CXC chemokine that signals through the CXCR2 receptor. It is expressed in monocytes, platelets, endothelial cells, and mast cells. ENA-78/LIX is a chemoattractant for neutrophils. The three naturally occurring variants of human ENA-78, ENA 5-78, ENA 9-78 and ENA 10-78, contain 74, 70, and 69 amino acid residues, respectively, and possess the same biological activity. ENA-78/LIX contains the four conserved cysteine residues present in CXC chemokines, and also contains the 'ELR' motif common to CXC chemokine that bind to the CXCR1 and CXCR2 receptors. Synonym: LIX/CXCL5 (93a.a.), Mouse. Formulation: Lyophilized from a 0.2µm filtered concentrated solution in 20mM PB, pH 7.4, 150mM NaCl.
- 分子量
- 9.8 kDa, a single, non-glycosylated polypeptide chain containing 93 amino acids.
- 途径
- Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity
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