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CXCL5 蛋白

This CXCL5 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN988115
发货至: 中国

Quick Overview for CXCL5 蛋白 (ABIN988115)

抗原

See all CXCL5 蛋白
CXCL5 (Chemokine (C-X-C Motif) Ligand 5 (CXCL5))

生物活性

Active

宿主

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小鼠

资源

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大肠杆菌(E. Coli)

纯度

> 97 % by SDS-PAGE and HPLC analyses.
  • 序列

    APSSVIAATE LRCVCLTVTP KINPKLIANL EVIPAGPQCP TVEVIAKLKN QKEVCLDPEA PVIKKIIIQK ILGSDKKKAK RNALAVERTA SV

    产品特性

    Fully biologically active when compared to standard. The ED50 determined by a chemotaxis bioassay using human peripheral blood neutrophils is less than 100 ng/ml, corresponding to a specific activity of >, 1.0 × 104 IU/mg.

    内毒素水平

    Level Less than 1EU/µg of rMuLIX/CXCL5 as determined by LAL method
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at < -20 °C. Further dilutions should be made in appropriate buffered solutions.

    储存条件

    4 °C
  • 抗原

    CXCL5 (Chemokine (C-X-C Motif) Ligand 5 (CXCL5))

    别名

    LIX/CXCL5

    背景

    The mouse homolog of ENA-78 is called LIX. ENA-78/LIX is a CXC chemokine that signals through the CXCR2 receptor. It is expressed in monocytes, platelets, endothelial cells, and mast cells. ENA-78/LIX is a chemoattractant for neutrophils. The three naturally occurring variants of human ENA-78, ENA 5-78, ENA 9-78 and ENA 10-78, contain 74, 70, and 69 amino acid residues, respectively, and possess the same biological activity. ENA-78/LIX contains the four conserved cysteine residues present in CXC chemokines, and also contains the 'ELR' motif common to CXC chemokine that bind to the CXCR1 and CXCR2 receptors. Synonym: LIX/CXCL5 (93a.a.), Mouse. Formulation: Lyophilized from a 0.2µm filtered concentrated solution in 20mM PB, pH 7.4, 150mM NaCl.

    分子量

    9.8 kDa, a single, non-glycosylated polypeptide chain containing 93 amino acids.

    途径

    Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity
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