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IL-20 蛋白

This not_set IL-20 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN988057
发货至: 中国
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Quick Overview for IL-20 蛋白 (ABIN988057)

抗原

See all IL-20 (IL20) 蛋白
IL-20 (IL20) (Interleukin 20 (IL20))

生物活性

Active

宿主

  • 13
  • 6
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  • 1

资源

  • 15
  • 5
  • 1
大肠杆菌(E. Coli)

纯度

> 95 % by SDS-PAGE and HPLC analyses.
  • 序列

    MLKTLNLGSC VIATNLQEIR NGFSEIRGSV QAKDGNIDIR ILRRTESLQD TKPANRCCLL RHLLRLYLDR VFKNYQTPDH YTLRKISSLA NSFLTIKKDL RLCHAHMTCH CGEEAMKKYS QILSHFEKLE PQAAVVKALG ELDILLQWME ET

    产品特性

    Fully biologically active when compared to standard. The ED50 determined by a cell proliferation assay using human IL-20Ralpha and human IL-20Rbeta co-transfected murine BaF3 pro-B cells is less than 0.6 ng/ml, corresponding to a specific activity of >, 1.7 × 106 IU/mg.

    内毒素水平

    Level Less than 1EU/µg of rHuIL-20 as determined by LAL method
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at < -20 °C. Further dilutions should be made in appropriate buffered solutions.

    储存条件

    4 °C
  • 抗原

    IL-20 (IL20) (Interleukin 20 (IL20))

    别名

    Interleukin-20 (IL-20)

    背景

    IL-20 is a member of the IL-10 family of regulatory cytokines which includes IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. Members of this family share partial homology in their amino acid sequences but they are dissimilar in their biological functions. IL-20 is a hematopoietic growth factor capable of stimulating colony formation by CD34+ multipotential progenitors, but not by other progenitor cells. IL-20 signals through a receptor system composed of type I IL-20R-ª and type II IL-20R-beta. Over-expression of IL-20 in keratinocytes expressing both receptor subunits has been implicated in the induction of inflammatory skin disease. Synonym: Interleukin-20 (IL-20), Human. Formulation: Lyophilized from a 0.2µm filtered concentrated solution in PBS, pH 7.4.

    分子量

    Approximately 17.6 kDa, a single non-glycosylated polypeptide chain containing 153 amino acids.

    途径

    Protein targeting to Nucleus
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