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IL17F 蛋白

This IL17F protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN988050
发货至: 中国

Quick Overview for IL17F 蛋白 (ABIN988050)

抗原

See all IL17F 蛋白
IL17F (Interleukin 17F (IL17F))

生物活性

Active

宿主

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资源

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大肠杆菌(E. Coli)

纯度

> 95 % by SDS-PAGE and HPLC analyses.
  • 序列

    MRKIPKVGHT FFQKPESCPP VPGGSMKLDI GIINENQRVS MSRNIESRST SPWNYTVTWD PNRYPSEVVQ AQCRNLGCIN AQGKEDISMN SVPIQQETLV VRRKHQGCSV SFQLEKVLVT VGCTCVTPVI HHV

    产品特性

    Fully biologically active when compared to standard. The ED50 determined by inducing IL-6 secretion of murine NIH/3T3 cells is less than 15 ng/ml, corresponding to a specific activity of >, 6.7 × 104 IU/mg.

    内毒素水平

    Level Less than 1EU/µg of rHuIL-17F as determined by LAL method
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in 4 mM HCl to a concentration of 0.1mg/ml. Stock solutions should be apportioned into working aliquots and stored at < -20 °C. Further dilutions should be made in appropriate buffered solutions.

    储存条件

    4 °C
  • 抗原

    IL17F (Interleukin 17F (IL17F))

    别名

    Interleukin-17F (IL-17F)

    背景

    Human IL-17F is synthesized as a 153 aa precursor with a 20 aa signal sequence and a 133 aa mature region. Like IL-17A, IL-17F contains one potential site for N-linked glycosylation. IL-17A and IL-17F share 50% aa sequence identity. IL17-F homodimer is produced by an activated subset of CD4+ T cells, termed Th17. IL17-F has been shown to stimulate proliferation and activation of T-cells and PBMCs. IL-17F also regulates cartilage matrix turnover and inhibits angiogenesis. Synonym: Interleukin-17F (IL-17F), Human. Formulation: Lyophilized from a 0.2µm filtered concentrated solution in PBS, pH 7.4.

    分子量

    A disulfide-linked homodimer of 30.1kDa, consisting of two 134 amino acid polypeptide chains.

    途径

    Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity
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