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IL-15 蛋白

IL15 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 98.0 % as determined by:(a)Analysis by RP-HPLC(b)Anion-exchange FPLC(c)Analysis by reducing and non-reducing SDS-PAGE Silver Stained gel. Active
产品编号 ABIN988042
发货至: 中国
  • 抗原 See all IL-15 (IL15) 蛋白
    IL-15 (IL15) (Interleukin 15 (IL15))
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 23
    • 7
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    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
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    • 1
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    资源
    • 35
    • 10
    • 10
    • 2
    • 2
    大肠杆菌(E. Coli)
    序列
    MNWVNVISDL KKIEDLIQSM HIDATLYTES DVHPSCKVTA MKCFLLELQV ISHESGDTDI HDTVENLIIL ANNILSSNGN ITESGCKECE ELEEKNIKEF LQSFVHIVQM FINTanalys is The sequence of the first five N-terminal amino acids was determined and was found to be Asn-Trp-Val-Asn-Val. p to grams level.
    产品特性
    The ED50 as determined by the dose-dependant stimulation of the proliferation of CTLL-2 was found to be
    纯度
    > 98.0 % as determined by:(a)Analysis by RP-HPLC(b)Anion-exchange FPLC(c)Analysis by reducing and non-reducing SDS-PAGE Silver Stained gel.
    内毒素水平
    Level Less than 0.1 ng/µg (1 IEU/µg) of Recombinant Human Interleukin 15 (IL-15
    Top Product
    Discover our top product IL15 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    It is recommended to reconstitute the lyophilized Recombinant Human Interleukin 15 (IL-15) in sterile 18 M-omega-cm H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. Quantitation Protein quantitation was carried out by two independent methods:1. UV spectroscopy at 280 nm using the absorbency value of 0.55 as the extinction coefficient for a 0.1% (1 mg/ml) solution. This value is calculated by the PC GENE computer analysis program of protein sequences (IntelliGenetics).2. Analysis by RP-HPLC, using a calibrated solution of IL-15 as a Reference Standard.
    储存条件
    -20 °C
  • Stone, Chervin, Schreiber, Kranz: "Design and characterization of a protein superagonist of IL-15 fused with IL-15R? and a high-affinity T cell receptor." in: Biotechnology progress, Vol. 28, Issue 6, pp. 1588-97, (2012) (PubMed).

  • 抗原
    IL-15 (IL15) (Interleukin 15 (IL15))
    别名
    Interleukin-15 (IL-15) (IL15 产品)
    别名
    IL15 Protein, AI503618 Protein, IL-15 Protein, interleukin 15 Protein, IL15 Protein, Il15 Protein
    背景
    Interleukin 15 (IL-15) is a cytokine that possesses a variety of biological functions. Interleukin 15 (IL-15) stimulates the proliferation of T-lymphocytes, which requires interaction of IL-15 with components of IL-2R, including IL-2R and probably IL-2R gamma, but not IL-2R. Recombinant Human Interleukin 15 (IL-15) produced in E. coli is a single, non-glycosylated polypeptide chain containing 114 amino acids and having a molecular mass of 12,774 Da. Synonym: rHuIL-15, rHuIL15, Interleukin-15, Interleukin1. Formulation: The protein was lyophilized after extensive dialysis against 20mM PB, pH7.5, 150mM NaCl buffer.
    分子量
    12,774 Da
    途径
    JAK/STAT Signaling, Glycosaminoglycan Metabolic Process
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