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GRO gamma 蛋白

This GRO gamma protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN987897
发货至: 中国

Quick Overview for GRO gamma 蛋白 (ABIN987897)

抗原

See all GRO gamma 蛋白
GRO gamma (Growth Regulated Oncogene gamma (GRO gamma))

生物活性

Active

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资源

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大肠杆菌(E. Coli)

纯度

> 97 % by SDS-PAGE and HPLC analyses.
  • 序列

    ASVVTELRCQ CLQTLQGIHL KNIQSVNVRS PGPHCAQTEV IATLKNGKKA CLNPASPMVQ KIIEKILNKG ST

    产品特性

    Fully biologically active when compared to standard. The ED50 determined by a chemotaxis bioassay using human CXCR2 transfected human 293 cells is less than 100 ng/ml, corresponding to a specific activity of >, 1.0 × 104 IU/mg.

    内毒素水平

    Level Less than 1EU/µg of rHuGRO-gamma/CXCL3 as determined by LAL method
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20 °C. Further dilutions should be made in appropriate buffered solutions.

    储存条件

    4 °C
  • 抗原

    GRO gamma (Growth Regulated Oncogene gamma (GRO gamma))

    别名

    GRO-gamma/CXCL3

    背景

    The three GRO cDNAs encode 107 amino acid precursor proteins from which the N-terminal 34 amino acid residues are cleaved to generate the mature GROs. There are no potential N-linked glycosylation sites in the amino acid sequences. GRO expression is inducible by serum or PDGF and/or by a variety of inflammatory mediators, such as IL-1 and TNF, in monocytes, fibroblasts, melanocytes and epithelial cells. In certain tumor cell lines, GRO is expressed constitutively.Similar to other alpha chemokines, the three GRO proteins are potent neutrophil attractants and activators. In addition, these chemokines are also active toward basophils. All three GROs can bind with high affinity to the IL-8 receptor type B. Synonym: GRO-gamma/CXCL3, Human. Formulation: Lyophilized from a 0.2µm filtered concentrated solution in 20mM PB, pH 7.4, 50mM NaCl.

    分子量

    7.9 kDa, a single non-glycosylated polypeptide chain containing 73 amino acids.
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