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GM-CSF 蛋白

CSF2 宿主: 猕猴 宿主: 大肠杆菌(E. Coli) > 98 % by SDS-PAGE and HPLC analyses. Active
产品编号 ABIN987887
发货至: 中国
  • 抗原 See all GM-CSF (CSF2) 蛋白
    GM-CSF (CSF2) (Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2))
    生物活性
    Active
    宿主
    • 31
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    猕猴
    资源
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    大肠杆菌(E. Coli)
    序列
    APARSPSPGT QPWEHVNAIQ EARRLLNLSR DTAAEMNKTV EVVSEMFDLQ EPSCLQTRLE LYKQGLQGSL TKLKGPLTMM ASHYKQHCPP TPETSCATQI ITFQSFKENL KDFLLVIPFD CWEPVQ
    产品特性
    Fully biologically active when compared to standard. The ED50 as calculated by the dose-dependant stimulation of the proliferation of human TF-1 cells is less than 0.1 ng/ml, corresponding to aof 1.0×107 IU/mg
    纯度
    > 98 % by SDS-PAGE and HPLC analyses.
    内毒素水平
    Level Less than 1EU/µg of rRhGM-CSF as determined by LAL method
    Top Product
    Discover our top product CSF2 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at
    储存条件
    4 °C
  • 抗原
    GM-CSF (CSF2) (Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2))
    别名
    Granulocyte Macrophage Colony Stimulating Factor (GM-CSF) (CSF2 产品)
    背景
    GM-CSF was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. It is produced by a number of different cell types (including activated T cells, B cells, macrophages, mast cells, endothelial cells and fibroblasts) in response to cytokine or immune and inflammatory stimuli. Besides granulocyte-macrophage progenitors, GM-CSF is also a growth factor for erythroid, megakaryocyte and eosinophil progenitors. On mature hematopoietic cells, GM-CSF is a survival factor for and activates the effector functions of granulocytes, monocytes/macrophages and eosinophils. Synonym: Granulocyte Macrophage Colony Stimulating Factor (GM-CSF), Rhesus Macaque. Formulation: Lyophilized from a 0.2µm filtered concentratedcsolution in PBS, pH 7.4.
    分子量
    Approximately 14.4 kDa, a single non-glycosylated polypeptide chain containing 127 amino acids.
    途径
    JAK/STAT Signaling, Cellular Response to Molecule of Bacterial Origin
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