CX3CL1 蛋白
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- 抗原 See all CX3CL1 蛋白
- CX3CL1 (Chemokine (C-X3-C Motif) Ligand 1 (CX3CL1))
- 生物活性
- Active
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 序列
- QHHGVTKCNI TCSKMTSKIP VALLIHYQQN QASCGKRAII LETRQHRLFC ADPKEQWVKD AMQHLDRQAA ALTRN
- 产品特性
- Fully biologically active when compared to standard. The ED50 determined by a chemotaxis bioassay using human T-lymphocytes is less than 10 ng/ml, corresponding to a specific activity of >, 1.0 × 105 IU/mg.
- 纯度
- > 97 % by SDS-PAGE and HPLC analyses.
- 内毒素水平
- Level Less than 1EU/µg of rHuFractalkine/CX3CL1 as determined by LAL method
- Top Product
- Discover our top product CX3CL1 蛋白
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Chemokine (C-X3-C Motif) Ligand 1 (CX3CL1) (AA 25-341) protein (His tag)
CX3CL1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Chemokine (C-X3-C Motif) Ligand 1 (CX3CL1) (AA 25-336) protein (His tag)CX3CL1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Chemokine (C-X3-C Motif) Ligand 1 (CX3CL1) (AA 25-341) protein (His tag)CX3CL1 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Chemokine (C-X3-C Motif) Ligand 1 (CX3CL1) (AA 25-336) protein (His-Avi Tag,Biotin)CX3CL1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Chemokine (C-X3-C Motif) Ligand 1 (CX3CL1) (Active) proteinCX3CL1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
Chemokine (C-X3-C Motif) Ligand 1 (CX3CL1) (AA 25-100) protein (His tag)CX3CL1 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Chemokine (C-X3-C Motif) Ligand 1 (CX3CL1) (AA 76-182) protein (His tag)CX3CL1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Chemokine (C-X3-C Motif) Ligand 1 (CX3CL1) (AA 351-449) protein (GST tag)CX3CL1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Chemokine (C-X3-C Motif) Ligand 1 (CX3CL1) (AA 1-397) protein (GST tag)CX3CL1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Chemokine (C-X3-C Motif) Ligand 1 (CX3CL1) (AA 1-236) protein (GST tag)CX3CL1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20 °C. Further dilutions should be made in appropriate buffered solutions.
- 储存条件
- 4 °C
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- 抗原
- CX3CL1 (Chemokine (C-X3-C Motif) Ligand 1 (CX3CL1))
- 别名
- Fractalkine/CX3CL1 (CX3CL1 产品)
- 背景
- Fractalkine, also named neurotactin, is a novel chemokine recently identified through bioinformatics. Fractalkine has a unique C-X3-C cysteine motif near the amino-terminus and is the first member of a fourth branch of the chemokine superfamily. Unlike other known chemokines, fractalkine is a type 1 membrane protein containing a chemokine domain tethered on a long mucin-like stalk. Human fractalkine cDNA encodes a 397 amino acid (aa) residue membrane protein with a 24 aa residue predicted signal peptide, a 76 aa residue chemokine domain, a 241 aa residue stalk region containing 17 degenerate mucin-like repeats, a 19 aa residue transmembrane segment and a 37 aa residue cytoplasmic domain. The extracellular domain of human fractalkine can be released, possibly by proteolysis at the dibasic cleavage site proximal to the membrane, to generate soluble fractalkine. The soluble chemokine domain of human fractalkine was reported to be chemotactic for T cells and monocytes while the soluble chemokine domain of mouse fractalkine was reported to chemoattract neutrophils and T-lymphocytes but not monocytes. Synonym: Fractalkine/CX3CL1, Human. Formulation: Lyophilized from a 0.2µm filtered concentrated solution in 20mM PB, pH 7.4, 50mM NaCl.
- 分子量
- 8.5 kDa, a single non-glycosylated polypeptide chain containing 76 amino acids and comprises only the chemokine domain of Human Fractalkine.
- 途径
- Synaptic Membrane
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