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CCL21 蛋白

This CCL21 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN987838
发货至: 中国

Quick Overview for CCL21 蛋白 (ABIN987838)

抗原

See all CCL21 蛋白
CCL21 (Chemokine (C-C Motif) Ligand 21 (CCL21))

生物活性

Active

宿主

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资源

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大肠杆菌(E. Coli)

纯度

> 97 % by SDS-PAGE and HPLC analyses.
  • 序列

    SDGGAQDCCL KYSQRKIPAK VVRSYRKQEP SLGCSIPAIL FLPRKRSQAE LCADPKELWV QQLMQHLDKT PSPQKPAQGC RKDRGASKTG KKGKGSKGCR KTERSQTPKG

    产品特性

    Fully biologically active when compared to standard. The ED50 determined by a chemotaxis bioassay using human peripheral blood T-lymphocytes is less than 600 ng/ml, corresponding to a specific activity of >, 1.7 × 103 IU/mg.

    内毒素水平

    Level Less than 1EU/µg of rHuExodus/CCL21 as determined by LAL method
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at < -20 °C. Further dilutions should be made in appropriate buffered solutions.

    储存条件

    4 °C
  • 抗原

    CCL21 (Chemokine (C-C Motif) Ligand 21 (CCL21))

    别名

    Exodus-2/CCL21

    背景

    Exodus-2/CCL21 is a novel CC chemokine discovered independently by three groups from the EST database, and shows 21-33% identity to other CC chemokines. Exodus-2 contains the four conserved cysteines characteristic of beta chemokines plus two additional cysteines in its unusually long carboxylterminal domain. It is expressed in lymph nodes of certain endothelial cells, and in the spleen and appendix. Exodus-2 chemoattracts T and B lymphocytes and inhibits hematopoiesis. Synonym: Exodus-2/CCL21, Human. Formulation: Lyophilized from a 0.2µm filtered concentrated solution in 20mM PB, pH 7.4,150mM NaCl.

    分子量

    12.2 kDa, a single, non-glycosylated polypeptide chain containing 111 amino acids.

    途径

    Regulation of Actin Filament Polymerization
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