Exendin 4 蛋白
宿主: Gila monster
宿主: 大肠杆菌（E. Coli）
Recombinant
> 96 % by SDS-PAGE and HPLC analyses.
Active
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- 抗原 See all Exendin 4 products
- Exendin 4
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- Gila monster
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资源
- 大肠杆菌（E. Coli）
- 序列
- HGEGTFTSDL SKQMEEEAVR LFIEWLKNGG PSSGAPPP
- 产品特性
- 1. Regulates Glucose levels rapidly 2. Reduces Insulin resistence 3. Reduces Glucagon 4. Reduces HbA1c 5. Stimulates beta cell growth which stimulates insulin production.
- 纯度
- > 96 % by SDS-PAGE and HPLC analyses.
- 内毒素水平
- Level Less than 10EU/mg of rExendin-4 as determined by LAL method
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20 °C. Further dilutions should be made in appropriate buffered solutions.
- 储存条件
- 4 °C
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- 抗原
- Exendin 4
- 别名
- Exendin-4 (Exendin 4 产品)
- 背景
- Exendin-4 is a novel 39-amino acid peptide isolated from the venom of the Gila monster Heloderma suspectum. It shares 53% sequence homology with GLP-17-36amide and interacts with the same membrane receptor. Exendin-4 enhances glucose-dependent insulin secretion, suppresses inappropriately elevated glucagon secretion, and slows gastric emptying in vivo. It also promotes Ã-cell proliferation and neogenesis in vitro and in animal models. Recombinant Exendin-4 is E. coli expression of a synthetic DNA squence encoding the 39 amino acid of Exendin-4. Synonym: Exendin-4. Formulation: Lyophilized from a 0.2um filtered solution of 20mM PBS, pH 7.0, containing 4% mannitol.
- 分子量
- Approximately 4.2 kDa, a single non-glycosylated polypeptide chain containing 39 amino acids.
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