CXCL16 蛋白
Quick Overview for CXCL16 蛋白 (ABIN987799)
抗原
See all CXCL16 蛋白生物活性
宿主
资源
纯度
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序列
- NQGSVAGSCS CDRTISSGTQ IPQGTLDHIR KYLKAFHRCP FFIRFQLQSK SVCGGSQDQW VRELVDCFER KECGTGHGKS FHHQKHL
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产品特性
- Fully biologically active when compared to standard. The ED50 determined by a chemotaxis bioassay using murine lymphocytes is less than 1000 ng/ml, corresponding to a specific activity of >, 1.0 × 103 IU/mg.
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内毒素水平
- Level Less than 1EU/µg of rMuCXCL16 as determined by LAL method
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Chemokine (C-X-C Motif) Ligand 16 (CXCL16) (AA 27-201) protein (Fc Tag)
CXCL16 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC
Chemokine (C-X-C Motif) Ligand 16 (CXCL16) (Active) proteinCXCL16 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
Chemokine (C-X-C Motif) Ligand 16 (CXCL16) protein (His tag)CXCL16 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
Chemokine (C-X-C Motif) Ligand 16 (CXCL16) (AA 30-205) protein (Fc Tag)CXCL16 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Chemokine (C-X-C Motif) Ligand 16 (CXCL16) (AA 27-114) protein (His tag)CXCL16 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Chemokine (C-X-C Motif) Ligand 16 (CXCL16) (AA 49-273) protein (GST tag)CXCL16 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Chemokine (C-X-C Motif) Ligand 16 (CXCL16) (AA 27-198), (partial) protein (His tag)CXCL16 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant 90 % SDS, ELISA
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20 °C. Further dilutions should be made in appropriate buffered solutions.
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储存条件
- 4 °C
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- CXCL16 (Chemokine (C-X-C Motif) Ligand 16 (CXCL16))
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别名
- CXCL16
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背景
- Mouse CXCL16 (CXC chemokine 16) is a nonELR motifcontaining CXC chemokine with a transmembrane domain. CX3CL1/Fractalkine and CXCL16 are the only two transmembrane chemokines within the superfamily. Mouse CXCL16 cDNA encodes a 246 amino acid (aa) precursor protein with a putative 26 aa residue signal peptide,an 88 aa residue chemokine domain, an 87 aa residue mucinlike spacer region, a 22 aa residue transmembrane domain, and a 23 aa residue cytoplasmic tail. Mouse and human CXCL16 share 49% overall aa identity and 70% similarity in the chemokine domains. Mouse CXCL16 is produced by dendritic cells in lymphoid organ T cell zones and by cells in the splenic red pulp both as membranebound and soluble forms. Based on northern blot analysis,CXCL16 is also expressed in some nonlymphoid tissues such as lung, small intestine and kidney. The receptor for CXCL16 has been identified as CXCR6/Bonzo (STRL33 and TYMSTR), a receptor previously shown to be a coreceptor for HIV entry.CXCR6 is expressed on naive CD8 cells, naturalkiller T cells and activated CD8 and CD4 T cells. Synonym: CXCL16, Mouse. Formulation: Lyophilized from a 0.2µm filtered concentrated solution in PBS.
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分子量
- Recombinant murine CXCL16 is a 9.9 kDa protein containing 88 amino acid residues.
抗原
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