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Thrombopoietin Protein (THPO)

This Recombinant Thrombopoietin protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN935857
发货至: 中国

Quick Overview for Thrombopoietin Protein (THPO) (ABIN935857)

抗原

See all Thrombopoietin (THPO) 蛋白
Thrombopoietin (THPO)

蛋白类型

Recombinant

生物活性

Active

宿主

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资源

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大肠杆菌(E. Coli)

纯度

> 98 % pure
  • 序列

    SPVAPACDPR LLNKLLRDSH LLHSRLSQCP DVDPLSIPVL LPAVDFSLGE WKTQTEQSKA QDILGAVSLL LEGVMAARGQ LEPSCLSSLL GQLSGQVRLL LGALQGLLGT QLPLQGRTTA HKDPNALFLS LQQLLRGKVR FLLLVEGPTL CVRRTLPTTA VPSSTSQLLT LNKF

    产品特性

    Purified recombinant Human Thrombopoietin protein
    Expression System: E.coli
    Bioactivity: The ED50 as determined by the dose-dependent stimulation of the proliferation of human MO7e cells was found to be 1 x 10^6 units/mg.

    内毒素水平

    < 0.1 ng per µg (1 EU/µg).
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  • 应用备注

    Each Investigator should determine their own optimal working dilution for specific applications.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Restore in water to a concentration of 0.5 - 1.0 mg/mL.

    缓冲液

    Lyophilized from 10 mM Tris, pH 8.0.

    注意事项

    Avoid repeated freeze/thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
  • 抗原

    Thrombopoietin (THPO)

    别名

    Thrombopoietin

    背景

    TPO is a lineage specific growth factor, produced in the liver, kidney and skeletal muscle. It stimulates the proliferation and maturation of megakaryocytes, and promotes increased circulating levels of platelets in vivo. TPO signals through the c-mpl receptor and acts as an important regulator of circulating platelets. Human and Mouse TPO exhibits cross-species reactivity.
    Alternative Names: c-MPL Ligand protein, TPO protein, THPO protein, Megakaryocyte colony-stimulating factor protein, MGDF protein

    分子量

    18.7 kDa

    途径

    JAK/STAT Signaling, Hormone Activity
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