Purified recombinant Human Thrombopoietin protein Expression System: E.coli Bioactivity: The ED50 as determined by the dose-dependent stimulation of the proliferation of human MO7e cells was found to be ? 1.0 ng/mL, corresponding to a specific activity of ? 1 x 10^6 units/mg.
THPO
宿主: 人
宿主: 大肠杆菌(E. Coli)
Recombinant
>95 % as determined by SDS-PAGE
Func
Active
应用备注
Each Investigator should determine their own optimal working dilution for specific applications.
限制
仅限研究用
状态
Lyophilized
溶解方式
Reconstitute in water to a concentration of 0.1 - 1.0 mg/mL.
缓冲液
Lyophilized from 10 mM sodium citrate, pH 3.0.
注意事项
Avoid repeated freeze/thaw cycles.
储存条件
4 °C/-20 °C
储存方法
Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
抗原
Thrombopoietin (THPO)
别名
Thrombopoietin
背景
TPO is a lineage specific growth factor, produced in the liver, kidney and skeletal muscle. It stimulates the proliferation and maturation of megakaryocytes, and promotes increased circulating levels of platelets in vivo. TPO signals through the c-mpl receptor and acts as an important regulator of circulating platelets. Human and Mouse TPO exhibits cross-species reactivity. Alternative Names: TPO protein, THPO protein, MGDF protein, c-MPL Ligand protein, Megakaryocyte colony-stimulating factor protein