PLA2G7 蛋白
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北京 101111
Quick Overview for PLA2G7 蛋白 (ABIN935738)
抗原
See all PLA2G7 (Lp-PLA2) 蛋白蛋白类型
生物活性
宿主
资源
纯度
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序列
- FDWQYINPVA HMKSSAWVNK IQVLMAAASF GQTKIPRGNG PYSVGCTDLM FDHTNKGTFL RLYYPSQDND RLDTLWIPNK EYFWGLSKFL GTHWLMGNIL RLLFGSMTTP ANWNSPLRPG EKYPLVVFSH GLGAFRTLYS AIGIDLASHG FIVAAVEHRD RSASATYYFK DQSAAEIGDK SWLYLRTLKQ EEETHIRNEQ VRQRAKECSQ ALSLILDIDH GKPVKNALDL KFDMEQLKDS IDREKIAVIG HSFGGATVIQ TLSEDQRFRC GIALDAWMFP LGDEVYSRIP QPLFFINSEY FQYPANIIKM KKCYSPDKER KMITIRGSVH QNFADFTFAT GKIIGHMLKL KGDIDSNVAI DLSNKASLAF LQKHLGLHKD FDQWDCLIEG DDENLIPGTN INTTNQHIML QNSSGIEKYN
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产品特性
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Purified recombinant Human PAFAH protein
Expression System: 293 cells
Bioactivity: Measured by its ability to cleave a PAF analog in a chromogenic substrate linked assay. At a PAF-AH concentration of 10.0 µg/mL, 50 % cleavage was achieved at an incubation time of approximately 2 minutes. -
内毒素水平
- < 0.1 ng per µg (1 EU/µg).
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Lipoprotein-Associated phospholipase A2 (Lp-PLA2) (AA 22-440) protein (His tag)
Lp-PLA2 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Lipoprotein-Associated phospholipase A2 (Lp-PLA2) (AA 22-441) protein (His-IF2DI Tag)Lp-PLA2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Lipoprotein-Associated phospholipase A2 (Lp-PLA2) (AA 22-441) protein (GST tag)Lp-PLA2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Lipoprotein-Associated phospholipase A2 (Lp-PLA2) (AA 47-441) protein (His tag)Lp-PLA2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 85 % SDS
Lipoprotein-Associated phospholipase A2 (Lp-PLA2) protein (His tag)Lp-PLA2 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- Supplied as a lyophilized powder.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- PLA2G7 (Lp-PLA2) (Lipoprotein-Associated phospholipase A2 (Lp-PLA2))
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别名
- PAFAH
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背景
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Platelet Activating Factor (PAF) is a biologically active phospholipid, which exerts primarily proinflammatory activities by specifically signaling through G-protein-coupled receptors on platelets, neutrophils, and monocytes. Platelet Activating Factor Acetylhydrolase (PAF-AH) is a secreted protein that mediates PAF activity by specifically catalyzing hydrolysis of the "sn2" ester bond, resulting in the conversion of PAF to the biologically inactive lyso-PAF. PAF-AH can also interact with LDL particles to induce the hydrolysis of LDL associated, oxidized phospholipids, generating lysophosphatidylcholine (lyso-PC) and other lysophospholipids.
Alternative Names: PAF 2-acylhydrolase protein, PAF acetylhydrolase protein, LDL-associated phospholipase A2 protein, LDL-PLA2 protein, 2-acetyl-1-alkylglycerophosphocholine esterase protein, 1-alkyl-2-acetylglycerophosphocholine esterase protein -
分子量
- 47-55 kDa
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途径
- Peptide Hormone Metabolism
抗原
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