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Platelet-Derived Growth Factor CC (PDGFCC) (Active) 蛋白

PDGFCC 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 98 % pure Active
产品编号 ABIN935736
发货至: 中国
  • 抗原 See all Platelet-Derived Growth Factor CC (PDGFCC) 蛋白
    Platelet-Derived Growth Factor CC (PDGFCC)
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    资源
    大肠杆菌(E. Coli)
    序列
    MVVDLNLLTE EVRLYSCTPR NFSVSIREEL KRTDTIFWPG CLLVKRCGGN CACCLHNCNE CQCVPSKVTK KYHEVLQLRP KTGVRGLHKS LTDVALEHHE ECDCVCRGST GG
    产品特性
    Purified recombinant Human PDGF CC protein
    Expression System: E.coli
    Bioactivity: Determined by the dose-dependent stimulation of the proliferation of Balb/c 3T3 cells. The expected The ED50 for this effect is 15-20 ng/mL.
    纯度
    > 98 % pure
    内毒素水平
    < 0.1 ng per µg (1 EU/µg).
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Supplied as a lyophilized powder.
    注意事项
    Avoid repeated freeze/thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
  • 抗原
    Platelet-Derived Growth Factor CC (PDGFCC)
    别名
    PDGF CC (PDGFCC 产品)
    别名
    1110064L01Rik Protein, AI647969 Protein, PDGF-C Protein, SCDGF Protein, platelet-derived growth factor, C polypeptide Protein, platelet derived growth factor C Protein, Pdgfc Protein
    背景
    The platelet-derived growth factor (PDGF) family of heparin-binding growth factors consists of five known members, denoted PDGF-AA, PDGF-BB, PDGF-AB, PDGF-CC and PDGF-DD. The mature and active form of these proteins, an anti-parallel disulfide-linked dimer of two 12-14 kDa polypeptide chains, is obtained through proteolytic processing of biologically inactive precursor proteins, which contain an N-terminal CUB domain and a PDGF/VEGF homologous domain. The PDGFs interact with two related protein tyrosine kinase receptors, PDGFR-a and PDGFR-beta, and are potent mitogens for a variety of cell types, including smooth muscle cells, connective tissue cells, bone and cartilage cells, and certain tumor cells.
    Alternative Names: Osteosarcoma-derived Growth Factor protein, Platelet-Derived Growth Factor-CC protein, ODGF protein, Glioma-derived growth factor protein, PCGF protein, GDGF protein
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