PDGF-AA Homodimer (Active) 蛋白
This Recombinant PDGF-AA Homodimer protein is expressed in 大肠杆菌（E. Coli）.
产品编号 ABIN935704
发货至:
中国
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Contact Info
Our Local Distributor
中国
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北京 101111
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Quick Overview for PDGF-AA Homodimer (Active) 蛋白 (ABIN935704)
抗原
PDGF-AA Homodimer
蛋白类型
Recombinant
生物活性
Active
宿主
人
资源
大肠杆菌（E. Coli）
纯度
> 98 % pure
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序列
- SIEEAVPAVC KTRTVIYEIP RSQVDPTSAN FLIWPPCVEV KRCTGCCNTS SVKCQPSRVH HRSVKVAKVE YVRKKPKLKE VQVRLEEHLE CACATTSLNP DYREEDTGRP RESGKKRKRK RLKPT
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产品特性
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Purified recombinant Human PDGF AA protein
Expression System: E.coli
Bioactivity: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by Balb/c 3T3 cells is ? 1 ng/mL, corresponding to a specific activity of ? 1 x 10^6 units/mg. -
内毒素水平
- < 0.1 ng per µg (1 EU/µg).
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PDGF-AA Homodimer protein
宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % SDS, WB, ELISA, IP
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstitute in 10 mM CH0 OOH to a concentration of 0.1 - 1.0 mg/mL.
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缓冲液
- Supplied lyophilized with no additives.
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储存液
- Without preservative
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- PDGF-AA Homodimer
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别名
- PDGF AA
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背景
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PDGFs are disulfide-linked dimers consisting of two 12.0-13.5 kDa polypeptide chains, designated PDGF-A and PDGF-B chains. The three naturally occurring PDGFs, PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. The PDGFs are stored in platelet a-granules and are released upon platelet activation. The PDGFs are involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. Two distinct signaling receptors used by PDGFs have been identified and named PDGFR-a and PDGFR-beta. PDGFR-a is high-affinity receptor for each of the three PDGF forms.
Alternative Names: Platelet-Derived Growth Factor-AA protein, ODGF protein, GDGF protein, Glioma-derived growth factor protein, Osteosarcoma-derived Growth Factor protein -
分子量
- 28.5 kDa
抗原
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