Myostatin Propeptide (Active) 蛋白
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北京 101111
Quick Overview for Myostatin Propeptide (Active) 蛋白 (ABIN935653)
抗原
蛋白类型
生物活性
宿主
资源
纯度
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序列
- MNENSEQKEN VEKEGLCNAC TWRQNTKSSR IEAIKIQILS KLRLETAPNI SKDVIRQLLP KAPPLRELID QYDVQRDDSS DGSLEDDDYH ATTETIITMP TESDFLMQVD GKPKCCFFKF SSKIQYNKVV KAQLWIYLRP VETPTTVFVQ ILRLIKPMKD GTRYTGIRSL KLDMNPGTGI WQSIDVKTVL QNWLKQPESN LGIEIKALDE NGHDLAVTFP GPGEDGLNPF LEVKVTDTPK RSRR
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产品特性
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Purified recombinant Human Myostatin Propeptide protein
Expression System: E.coli
Bioactivity: Determined by its ability to neutralize the Myostatin inhibitory effect of Mouse MPC-11 cells. The expected ED50 is 0.01-0.04 µg/mL in the presence of 50 ng/mL Myostatin. -
内毒素水平
- < 0.1 ng per µg (1 EU/µg).
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- Supplied as a lyophilized powder.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- Myostatin Propeptide
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背景
- Mature Myostatin is obtained by proteolytic processing of a biologically-inactive precursor protein, which contains an N-terminal propeptide of 243 amino acid residues. Myostatin Propeptide exhibits high binding affinity for myostatin and has been shown to be a potent inhibitor of Myostatin. Over-expression of myostatin propeptide in mice resulted in large increases (up to 200 %) in skeletal muscle mass, similar to those observed in Myostatin knockout mice.
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分子量
- 27.8 kDa
抗原
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