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MSTN 蛋白

This Recombinant MSTN protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN935645
发货至: 中国

Quick Overview for MSTN 蛋白 (ABIN935645)

抗原

See all MSTN 蛋白
MSTN (Myostatin (MSTN))

蛋白类型

Recombinant

生物活性

Active

宿主

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资源

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大肠杆菌(E. Coli)

纯度

> 98 % pure
  • 序列

    DFGLDCDEHS TESRCCRYPL TVDFEAFGWD WIIAPKRYKA NYCSGECEFV FLQKYPHTHL VHQANPRGSA GPCCTPTKMS PINMLYFNGK EQIIYGKIPA MVVDRCGCS

    产品特性

    Purified recombinant Human Myostatin protein
    Expression System: E.coli
    Contaminants: Supplied lyophilized with no additives.
    Bioactivity: Determined by its ability to inhibit the proliferation of MPC-11 cells. The expected ED50 for this effect is 17.0-25.0 ng/mL.

    内毒素水平

    < 0.1 ng per µg (1 EU/µg).
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  • 应用备注

    Each Investigator should determine their own optimal working dilution for specific applications.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Reconstitute with water to 0.1 - 1.0 mg/mL . Due to the solubility reasons the protein should be kept at low pH.

    缓冲液

    Lyophilized with no additives.

    储存液

    Without preservative

    注意事项

    Avoid repeated freeze/thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
  • 抗原

    MSTN (Myostatin (MSTN))

    别名

    Myostatin

    背景

    Myostatin is a TGF beta family member that acts as an inhibitor of skeletal muscle growth. This muscle-specific cytokine interacts with Activin type I and type II receptors, and suppresses myoblast proliferation by arresting cell-cycle in the G1 phase. Suppression of myostatin activity facilitates muscle formation and may be useful in reducing and/or preventing adiposity and type-2 diabetes. Myostatin activity can be blocked by the Activin-binding protein Follistatin, and by the propeptide of Myostatin.
    Alternative Names: GDF-8 protein

    分子量

    25 kDa
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