Midkine 蛋白
Quick Overview for Midkine 蛋白 (ABIN935627)
抗原
See all Midkine (MDK) 蛋白蛋白类型
生物活性
宿主
资源
纯度
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序列
- VAKKKDKVKK GGPGSECAEW AWGPCTPSSK DCGVGFREGT CGAQTQRIRC RVPCNWKKEF GADCKYKFEN WGACDGGTGT KVRQGTLKKA RYNAQCQETI RVTKPCTPKT KAKAKAKKGK GKD
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产品特性
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Purified recombinant Human Midkine protein
Expression System: E.coli
Bioactivity: Determined by its ability to chemoattract human neutrophils using a concentration range of 0.1-10.0 ng/mL. -
内毒素水平
- < 0.1 ng per µg (1 EU/µg).
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Midkine (Neurite Growth-Promoting Factor 2) (MDK) (Active) protein
MDK 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
Midkine (Neurite Growth-Promoting Factor 2) (MDK) (AA 23-140) protein (His tag)MDK 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by Tris-Bis PAGE
Midkine (Neurite Growth-Promoting Factor 2) (MDK) (AA 21-143) protein (His-Avi Tag)MDK 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by Tris-Bis PAGE
Midkine (Neurite Growth-Promoting Factor 2) (MDK) (AA 21-140) protein (His tag)MDK 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Midkine (Neurite Growth-Promoting Factor 2) (MDK) (AA 1-143) protein (GST tag)MDK 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Midkine (Neurite Growth-Promoting Factor 2) (MDK) (AA 21-143) protein (His tag)MDK 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % by SDS - PAGE SDS
Midkine (Neurite Growth-Promoting Factor 2) (MDK) (AA 21-143) protein (Fc Tag)MDK 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Midkine (Neurite Growth-Promoting Factor 2) (MDK) (AA 23-143) protein (Fc Tag)MDK 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstitute in water to a concentration of 0.1-1.0 mg/mL.
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缓冲液
- Lyophilized from PBS, pH 7.4.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- RT/-20 °C
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- Midkine (MDK) (Midkine (Neurite Growth-Promoting Factor 2) (MDK))
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别名
- Midkine
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背景
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Midkine (MK) and its functionally-related protein Pleiotrophin are heparin-binding neurotrophic factors that signal through the same receptor, known as anaplastic lymphoma kinase (ALK). MK plays an important regulatory role in epithelial-mesenchymal interactions during fetal development and in postnatal lung development. MK chemoattracts embryonic neurons, neutrophils and macrophages, and by signaling through the ALK receptor it exerts angiogenic, growth and survival activities during tumorgenesis.
Alternative Names: MK protein, NEGF-2 protein -
分子量
- 13.4 kDa
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途径
- RTK signaling, M Phase, Skeletal Muscle Fiber Development
抗原
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