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IL-13 蛋白

IL13 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 98 % pure Active
产品编号 ABIN935579
发货至: 中国
  • 抗原 See all IL-13 (IL13) 蛋白
    IL-13 (IL13) (Interleukin 13 (IL13))
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 25
    • 14
    • 4
    • 3
    • 3
    • 3
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    • 2
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    • 2
    • 1
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    资源
    • 28
    • 16
    • 8
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    • 2
    • 1
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    大肠杆菌(E. Coli)
    序列
    VRRSTSPPVA LRELIEELSN ITQDQKTSLC NSSIVWSVDI TAGGFCAALE SLTNISSCNA IHRTQRILNG LCNQKASDVA SSPPDTKIEV AQFISKLLNY SKQLFRYGH
    产品特性
    Purified recombinant Human IL13 protein
    Expression System: E.coli
    Bioactivity: The ED50 as determined by the dose-dependant stimulation of the proliferation of human TF-1 cells is 2.5 x 10^4 units/mg.
    纯度
    > 98 % pure
    内毒素水平
    < 0.1 ng per µg (1 EU/µg).
    Top Product
    Discover our top product IL13 蛋白
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Supplied as a lyophilized powder.
    注意事项
    Avoid repeated freeze/thaw cycles.
    储存条件
    RT/-20 °C
  • 抗原
    IL-13 (IL13) (Interleukin 13 (IL13))
    别名
    IL13 (IL13 产品)
    别名
    IL13 Protein, IL-13 Protein, P600 Protein, Il-13 Protein, L13 Protein, interleukin 13 Protein, IL13 Protein, Il13 Protein
    背景
    IL13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and also by mast cells and NK cells. Targeted deletion of IL13 in mice resulted in impaired Th2 cell development and indicated an important role for IL13 in the expulsion of gastrointestinal parasites. IL13 exerts anti-inflammatory effects on monocytes and macrophages and it inhibits the expression of inflammatory cytokines such as IL1beta, TNF-alpha, IL6 and IL8. IL13 has also been shown to enhance B cell proliferation and to induce isotype switching resulting in increased production of IgE. Blocking of IL13 activity inhibits the pathophysiology of asthma.
    Alternative Names: IL13, IL 13, IL-13, Interleukin 13 protein, Human P600 protein, IL 13 protein, Mouse protein, IL-13 protein, NC300 protein, IL-13 protein
    分子量
    11.9 kDa
    途径
    JAK/STAT Signaling, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport
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