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IL-10 蛋白

This Recombinant IL-10 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN935529
发货至: 中国

Quick Overview for IL-10 蛋白 (ABIN935529)

抗原

See all IL-10 (IL10) 蛋白
IL-10 (IL10) (Interleukin 10 (IL10))

蛋白类型

Recombinant

生物活性

Active

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大肠杆菌(E. Coli)

纯度

> 98 % pure
  • 序列

    SKGHSIKGDN NCTHFPVSQT HMLRELRAAF SQVKTFFQKK DQLDNIVLTD SLLQDFKGYL GCQALSEMIK FYLVEVMPQA ENHGPEIKEH LNSLGEKLKT LWIQLRRCHR FLPCENKSKA VEQVKNDFNK LQDKGVYKAM NEFDIFINCI EAYVTLKMKN

    产品特性

    Purified recombinant Human IL10 protein
    Expression System: E.coli
    Bioactivity: The ED50 as determined by the dose-dependent inhibition of antigen-specific T cell proliferation is less than 10ng/mL.

    内毒素水平

    < 0.1 ng per µg (1 EU/µg).
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  • 应用备注

    Each Investigator should determine their own optimal working dilution for specific applications.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Reconstitute in water to a concentration of 0.1 - 1.0 mg/mL.

    缓冲液

    Lyophilized from 20 mM Na3PO4, pH 7.0.

    注意事项

    Avoid repeated freeze/thaw cycles.

    储存条件

    RT/-20 °C
  • 抗原

    IL-10 (IL10) (Interleukin 10 (IL10))

    别名

    IL10

    背景

    IL10 is an immunosuppressive cytokine produced by a variety of mammalian cell types including macrophages, monocytes, T cells, B cells and keratinocytes. IL10 inhibits the expression of proinflammatory cytokines such as IL1 and TNFa. Like IL4, IL10 enhances humoral immune responses and attenuates cell-mediated immune reactions. Human IL10 active on Mouse cells, but Mouse IL10 is inactive on human cells.
    Alternative Names: CSIF protein, B-TCGF protein, TGIF protein, IL 10 protein, Interleukin 10 protein, IL-10 protein, IL10, IL 10, IL-10 protein, IL-10

    分子量

    18.7 kDa

    途径

    Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location, Cancer Immune Checkpoints
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