Purified recombinant Human ILGFBP1 protein Expression System: E.coli Bioactivity: Inhibition of IGF-I stimulated proliferation of NUC-1 cells: IC50 ~ 100 ng/mL Inhibition of serum-induced stimulation of DNA synthesis in chick embryo fibroblast primary cultures: IC50 (1 % serum) ~300 ng/mL.
纯度
> 98 % pure
应用备注
Each Investigator should determine their own optimal working dilution for specific applications.
限制
仅限研究用
状态
Lyophilized
溶解方式
Reconstitute in 20 mM CH3COOH at the stock concentration of not less than 0.1 mg/mL.
缓冲液
Supplied as a lyophilized powder.
注意事项
Avoid repeated freeze/thaw cycles.
储存条件
RT/-20 °C
抗原
ILGFBP1
背景
IGFBP1 is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. Alternative Names: ILGFBP-1, hIGFBP-1 protein, PP12 protein, ILGFBP1, ILGFBP 1, ILGFBP-1 protein, ILGFBP-1 protein, AFBP protein, ILGFBP 1 protein, IGF-BP25 protein, IGF-Binding Protein 1 protein, IBP-1 protein, IGFBP-1 protein, Insulin Like Growth Factor Binding Protein 1 protein