IL-13 蛋白
Quick Overview for IL-13 蛋白 (ABIN935475)
抗原
See all IL-13 (IL13) 蛋白蛋白类型
生物活性
宿主
资源
纯度
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序列
- MSPGPVPPST ALRELIEELV NITQNQKAPL CNGSMVWSIN LTAGMYCAAL ESLINVSGCS AIEKTQRMLS GFCPHKVSAG QFSSLHVRDT KIEVAQFVKD LLLHLKKLFR EGRFN
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产品特性
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Purified recombinant Human IL13 protein
Expression System: E.coli
Bioactivity: The ED50 as determined by the dose-dependent proliferation of TF-1 cells was ? 1.0 ng/mL, corresponding to a specific activity of ? 1 x 10^6 units/mg. -
内毒素水平
- < 0.1 ng per μg (1 EU/μg).
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Interleukin 13 (IL13) (AA 21-132) protein (His-Avi Tag)
IL13 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Tris-Bis PAGE
Interleukin 13 (IL13) (AA 21-132) protein (Fc Tag)IL13 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 13 (IL13) (AA 19-132) protein (His tag)IL13 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 13 (IL13) (AA 26-131) (Active) protein (His tag)IL13 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE Active
Interleukin 13 (IL13) (AA 21-132) protein (His-Avi Tag,Biotin)IL13 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Tris-Bis PAGE
Interleukin 13 (IL13) (AA 19-132) (Active) proteinIL13 宿主: 人 宿主: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE. Active
Interleukin 13 (IL13) (AA 21-132) (Active) protein (Fc Tag)IL13 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Interleukin 13 (IL13) (AA 21-132) (Active) protein (His tag,AVI tag,Biotin)IL13 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Interleukin 13 (IL13) protein (mFc Tag)IL13 宿主: 人 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE.
Interleukin 13 (IL13) (AA 22-131) protein (His tag)IL13 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstitute with sterile water not less than 100 μg/mL.
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缓冲液
- Lyophilized with no additives.
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储存液
- Without preservative
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- RT/-20 °C
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- IL-13 (IL13) (Interleukin 13 (IL13))
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别名
- IL13
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背景
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IL13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and also by mast cells and NK cells. Targeted deletion of IL13 in mice resulted in impaired Th2 cell development and indicated an important role for IL13 in the expulsion of gastrointestinal parasites. IL13 exerts anti-inflammatory effects on monocytes and macrophages and it inhibits the expression of inflammatory cytokines such as IL1beta, TNF-alpha, IL6 and IL8. IL13 has also been shown to enhance B cell proliferation and to induce isotype switching resulting in increased production of IgE. Blocking of IL13 activity inhibits the pathophysiology of asthma.
Alternative Names: IL-13 protein, IL13, NC300 protein, IL 13, Human P600 protein, Mouse protein, IL-13, IL-13 protein, IL 13 protein, Interleukin 13 protein -
分子量
- 12.5 kDa
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途径
- JAK/STAT Signaling, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport
抗原
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