GM-CSF 蛋白
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北京 101111
Quick Overview for GM-CSF 蛋白 (ABIN935394)
抗原
See all GM-CSF (CSF2) 蛋白蛋白类型
生物活性
宿主
资源
纯度
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序列
- MAPTRSPNPV TRPWKHVDAI KEALSLLNDM RALENEKNED VDIISNEFSI QRPTCVQTRL KLYKQGLRGN LTKLNGALTM IASHYQTNCP PTPETDCEIE VTTFEDFIKN LKGFLFDIPF DCWKPVQK
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产品特性
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Purified recombinant Human GM-CSF protein
Expression System: E.coli
Bioactivity: The ED50 was determined by the dose-dependent stimulation of the proliferation of Mouse FDC-P1 cells is 1.0 x 10^8 units/mg. -
内毒素水平
- < 0.1 ng per µg (1 EU/µg).
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- Lyophilized from 10 mM tris, pH 8.5.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- RT/-20 °C
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- GM-CSF (CSF2) (Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2))
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别名
- GM-CSF
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背景
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GM-CSF is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. It is produced in by endothelial cells, monocytes, fibroblasts and T-lymphocytes. GM-CSF inhibits neutrophil migration and enhances the functional activity of the mature end-cells. The human and Mouse molecules are species-specific and exhibit no cross-species reactivity.
Alternative Names: Granulocyte/Macrophage Colony-Stimulating Factor protein, MGI-1GM protein, GM-CSF protein, CSF-2 protein, pluripoietin-alpha protein -
分子量
- 14.5 kDa
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途径
- JAK/STAT Signaling, Cellular Response to Molecule of Bacterial Origin
抗原
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