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GDF3 蛋白

This Recombinant GDF3 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN935382
发货至: 中国

Quick Overview for GDF3 蛋白 (ABIN935382)

抗原

See all GDF3 蛋白
GDF3 (Growth Differentiation Factor 3 (GDF3))

蛋白类型

Recombinant

生物活性

Active

宿主

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资源

  • 5
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  • 1
大肠杆菌(E. Coli)

纯度

> 98 % pure
  • 序列

    AAIPVPKLSC KNLCHRHQLF INFRDLGWHK WIIAPKGFMA NYCHGECPFS LTISLNSSNY AFMQALMHAV DPEIPQAVCI PTKLSPISML YQDNNDNVIL RHYEDMVVDE CGCG

    产品特性

    Purified recombinant Human GDF3 protein
    Expression System: E.coli
    Bioactivity: Determined by its ability to inhibit induced alkaline phosphatase production by ATDC-5 chondrogenic cells. The ED50 for this effect is 100-150 ng/mL.

    内毒素水平

    < 0.1 ng per µg (1 EU/µg).
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  • 应用备注

    Each Investigator should determine their own optimal working dilution for specific applications.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Reconstitute in water to a concentration of 0.1-1.0 mg/mL. Keep pH below 5.0.

    缓冲液

    Supplied lyophilized with no additives.

    储存液

    Without preservative

    注意事项

    Avoid repeated freeze/thaw cycles.

    储存条件

    RT/-20 °C
  • 抗原

    GDF3 (Growth Differentiation Factor 3 (GDF3))

    别名

    GDF3

    背景

    GDF-3 is a member of the TGF beta superfamily of growth and differentiation factors, and is highly homologous to GDF-9. Unlike most TGF beta family members, GDF-3 and GDF-9 are not disulfide-linked dimers. GDF-3 is expressed in adult bone marrow, spleen, thymus, and adipose tissue. The expression of GDF-3 is upregulated in high-fat-fed wild-type FABP4/aP2 null mice and was associated with obesity, but not with the related hyperglycemia/hyperinsulinemia which characterizes Type 2 diabetes.
    Alternative Names: GDF 3 protein, GDF-3 protein, GDF-3, GDF3, Growth/Differentiation Factor-3 protein, GDF-3 protein, GDF 3

    分子量

    26 kDa
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