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GDF11 蛋白

This Recombinant GDF11 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN935381
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for GDF11 蛋白 (ABIN935381)

抗原

See all GDF11 蛋白
GDF11 (Growth Differentiation Factor 11 (GDF11))

蛋白类型

Recombinant

生物活性

Active

宿主

  • 7
  • 4
  • 2

资源

  • 8
  • 2
  • 1
大肠杆菌(E. Coli)

纯度

> 98 % pure
  • 序列

    NLGLDCDEHS SESRCCRYPL TVDFEAFGWD WIIAPKRYKA NYCSGQCEYM FMQKYPHTHL VQQANPRGSA GPCCTPTKMS PINMLYFNDK QQIIYGKIPG MVVDRCGCS

    产品特性

    Purified recombinant Human GDF11 protein
    Expression System: E.coli
    Bioactivity: The ED50 was determined by its ability to inhibit induced alkaline phosphatase production by ATDC-5 chondrogenic cells. The expected ED50 for this effect is 0.08-0.10 µg/mL.

    内毒素水平

    < 0.1 ng per µg (1 EU/µg).
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  • 应用备注

    Each Investigator should determine their own optimal working dilution for specific applications.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Reconstitute in water to a concentration of 0.1-1.0 mg/mL. Keep pH below 5.0.

    缓冲液

    Supplied lyophilized with no additives.

    储存液

    Without preservative

    注意事项

    Avoid repeated freeze/thaw cycles.

    储存条件

    RT/-20 °C
  • 抗原

    GDF11 (Growth Differentiation Factor 11 (GDF11))

    别名

    GDF11

    背景

    GDF-11 is a myostatin-homologous protein that acts as an inhibitor of nerve tissue growth. GDF-11 has been shown to suppress neurogenesis through a myostatin-like pathway, which involves arrest of progenitor cell-cycle in the G1 phase. Similarities between myostatin and GDF-11, which are 90 % identical in their amino acid sequence, suggests that the regulatory mechanisms responsible for maintaining proper tissue size during neural and muscular development might be the same.
    Alternative Names: BMP-11 protein, GDF 11 protein, GDF-11 protein, GDF-11 protein, GDF-11, Growth/Differentiation Factor-11 protein, GDF11, GDF 11

    分子量

    25 kDa
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