GDF11 蛋白
This Recombinant GDF11 protein is expressed in 大肠杆菌（E. Coli）.
Quick Overview for GDF11 蛋白 (ABIN935381)
抗原
See all GDF11 蛋白
GDF11
(Growth Differentiation Factor 11 (GDF11))
蛋白类型
Recombinant
生物活性
Active
宿主
人
资源
大肠杆菌（E. Coli）
纯度
> 98 % pure
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序列
- NLGLDCDEHS SESRCCRYPL TVDFEAFGWD WIIAPKRYKA NYCSGQCEYM FMQKYPHTHL VQQANPRGSA GPCCTPTKMS PINMLYFNDK QQIIYGKIPG MVVDRCGCS
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产品特性
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Purified recombinant Human GDF11 protein
Expression System: E.coli
Bioactivity: The ED50 was determined by its ability to inhibit induced alkaline phosphatase production by ATDC-5 chondrogenic cells. The expected ED50 for this effect is 0.08-0.10 µg/mL. -
内毒素水平
- < 0.1 ng per µg (1 EU/µg).
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstitute in water to a concentration of 0.1-1.0 mg/mL. Keep pH below 5.0.
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缓冲液
- Supplied lyophilized with no additives.
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储存液
- Without preservative
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- RT/-20 °C
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- GDF11 (Growth Differentiation Factor 11 (GDF11))
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别名
- GDF11
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背景
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GDF-11 is a myostatin-homologous protein that acts as an inhibitor of nerve tissue growth. GDF-11 has been shown to suppress neurogenesis through a myostatin-like pathway, which involves arrest of progenitor cell-cycle in the G1 phase. Similarities between myostatin and GDF-11, which are 90 % identical in their amino acid sequence, suggests that the regulatory mechanisms responsible for maintaining proper tissue size during neural and muscular development might be the same.
Alternative Names: BMP-11 protein, GDF 11 protein, GDF-11 protein, GDF-11 protein, GDF-11, Growth/Differentiation Factor-11 protein, GDF11, GDF 11 -
分子量
- 25 kDa
抗原
-
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