Purified recombinant Human GCSF protein Expression System: E.coli Bioactivity: The ED50 as determined by the dose-dependent stimulation of the proliferation of Mouse M-NFS-60 cells is ? 0.1 ng/mL, corresponding to a specific activity of ? 1 x 10^7 units/mg.
G-CSF is a hematopoietic growth factor that stimulates the development of committed progenitor cells to neutrophils and enhances the functional activities of the mature end-cell. It is produced in response to specific stimulation by a variety of cells including macrophages, fibroblasts, endothelial cells and bone marrow stroma. G-CSF is being used clinically to facilitate hematopoietic recovery after bone marrow transplantation. Human and Mouse G-CSF are cross-species reactive. Alternative Names: CSF-3 protein, Granulocyte Colony-Stimulating Factor protein, GM-CSF beta protein, MGI-1G protein, pluripoietin protein