CYR61 蛋白
Quick Overview for CYR61 蛋白 (ABIN935294)
抗原
See all CYR61 蛋白蛋白类型
生物活性
宿主
资源
纯度
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序列
- MTCPAACHCP LEAPKCAPGV GLVRDGCGCC KVCAKQLNED CSKTQPCDHT KGLECNFGAS STALKGICRA QSEGRPCEYN SRIYQNGESF QPNCKHQCTC IDGAVGCIPL CPQELSLPNL GCPNPRLVKV TGQCCEEWVC DEDSIKDPME DQDGLLGKEL GFDASEVELT RNNELIAVGK GSSLKRLPVF GMEPRILYNP LQGQKCIVQT TSWSQCSKTC GTGISTRVTN DNPECRLVKE TRICEVRPCG QPVYSSLKKG KKCSKTKKSP EPVRFTYAGC LSVKKYRPKY CGSCVDGRCC TPQLTRTVKM RFRCEDGETF SKNVMMIQSC KCNYNCPHAN EAAFPFYRLF NDIHKFRD
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产品特性
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Purified recombinant Human CYR61 protein
Expression System: E.coli
Bioactivity: Determined by the dose-dependent stimulation of the proliferation of Mouse 3T3 cells. The expected ED50 for this effect is 2.0-3.0 µg/mL. -
内毒素水平
- < 0.1 ng per µg (1 EU/µg).
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Cysteine-Rich, Angiogenic Inducer, 61 (CYR61) (AA 1-381) protein (GST tag)
CYR61 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Cysteine-Rich, Angiogenic Inducer, 61 (CYR61) (AA 25-381) protein (His tag)CYR61 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Cysteine-Rich, Angiogenic Inducer, 61 (CYR61) (AA 25-381) protein (GST tag)CYR61 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Cysteine-Rich, Angiogenic Inducer, 61 (CYR61) proteinCYR61 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % WB, SDS, ELISA, IP
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- Supplied as a lyophilized powder.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- CYR61 (Cysteine-Rich, Angiogenic Inducer, 61 (CYR61))
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别名
- CYR61
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背景
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CYR61 is a member of the CCN family of secreted cysteine rich regulatory proteins. CYR61 induces angiogenesis by stimulating the proliferation, migration, and adhesion of endothelial cells. Cell migration and adhesion are mediated through binding to specific cell surface integrins and to heparin sulfate proteoglycans. Increased expression of CYR61 is associated with several types of cancer, and correlates with the progression and estrogen independence of human breast cancers. Recombinant human CYR61 is a 39.5 kDa protein containing 357 amino acid residues. It is composed of four distinct structural domains (modules), the IGF binding protein (IGFBP) domain, the von Willebrand Factor C (VWFC) domain, the Thrombospondin type-I (TSP type-1) domain, and a C-terminal cysteine knot-like domain (CTCK).
Alternative Names: CYR61, CYR6-1 protein, CYR-61 protein, CYR 61, CYR 61 protein, CYR-61, CCN1 protein, GIGI protein protein -
途径
- Positive Regulation of Endopeptidase Activity, Growth Factor Binding
抗原
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