Purified recombinant Human BMP6 protein Expression System: HEK cells Bioactivity: Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 this effect is 0.03-0.06 µg/mL.
Each Investigator should determine their own optimal working dilution for specific applications.
限制
仅限研究用
状态
Lyophilized
溶解方式
Reconstitute in water to a concentration of 0.1-1.0 mg/mL.
缓冲液
Lyophilized from 10 mM Tris, pH 9.0.
注意事项
Avoid repeated freeze/thaw cycles.
储存条件
4 °C/-20 °C
储存方法
Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
抗原
BMP6
(Bone Morphogenetic Protein 6 (BMP6))
别名
BMP6
背景
TGF beta family members are key modulators of cell proliferation, differentiation, matrix synthesis, and apoptosis. As implied by their name, BMPs initiate, promote, and regulate the development, growth and remodeling of bone and cartilage. In addition to this role, BMPs are also involved in prenatal development and postnatal growth, remodeling and maintenance of a variety of other tissues and organs. Increasing evidence indicates that BMP-Smad signaling has a tumor suppressing activity and that BMPs can inhibit tumor growth. BMP-6 is abnormally expressed in breast cancer cell lines, however, its function in promoting breast cancer development is unknown. Alternative Names: BMP 6 protein, VGR protein, BMP6, Bone Morphogenetic protein 6 protein, BMP-6, BMP-6 protein, BMP-6 protein, BMP 6