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BMP6 蛋白

This Recombinant BMP6 protein is expressed in HEK-293 Cells.
产品编号 ABIN935246
发货至: 中国

Quick Overview for BMP6 蛋白 (ABIN935246)

抗原

See all BMP6 蛋白
BMP6 (Bone Morphogenetic Protein 6 (BMP6))

蛋白类型

Recombinant

生物活性

Active

宿主

  • 6
  • 3
  • 2

资源

  • 8
  • 3
HEK-293 Cells

纯度

> 95 % pure
  • 序列

    VSSASDYNSS ELKTACRKHE LYVSFQDLGW QDWIIAPKGY AANYCDGECS FPLNAHMNAT NHAIVQTLVH LMNPEYVPKP CCAPTKLNAI SVLYFDDNSN VILKKYRNMV VRACGCH

    产品特性

    Purified recombinant Human BMP6 protein
    Expression System: HEK cells
    Bioactivity: Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 this effect is 0.03-0.06 µg/mL.

    内毒素水平

    < 0.1 ng per µg (1 EU/µg).
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  • 应用备注

    Each Investigator should determine their own optimal working dilution for specific applications.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Reconstitute in water to a concentration of 0.1-1.0 mg/mL.

    缓冲液

    Lyophilized from 10 mM Tris, pH 9.0.

    注意事项

    Avoid repeated freeze/thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
  • 抗原

    BMP6 (Bone Morphogenetic Protein 6 (BMP6))

    别名

    BMP6

    背景

    TGF beta family members are key modulators of cell proliferation, differentiation, matrix synthesis, and apoptosis. As implied by their name, BMPs initiate, promote, and regulate the development, growth and remodeling of bone and cartilage. In addition to this role, BMPs are also involved in prenatal development and postnatal growth, remodeling and maintenance of a variety of other tissues and organs. Increasing evidence indicates that BMP-Smad signaling has a tumor suppressing activity and that BMPs can inhibit tumor growth. BMP-6 is abnormally expressed in breast cancer cell lines, however, its function in promoting breast cancer development is unknown.
    Alternative Names: BMP 6 protein, VGR protein, BMP6, Bone Morphogenetic protein 6 protein, BMP-6, BMP-6 protein, BMP-6 protein, BMP 6

    分子量

    26.2 kDa

    途径

    Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process
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