APOE 蛋白
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- 抗原 See all APOE 蛋白
- APOE (Apolipoprotein E (APOE))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 序列
- MKVEQAVETE PEPELRQQTE WQSGQRWELA LGRFWDYLRW VQTLSEQVQE ELLSSQVTQE LRALMDETMK ELKAYKSELE EQLTPVAEET RARLSKELQA AQARLGADME DVRGRLVQYR GEVQAMLGQS TEELRVRLAS HLRKLRKRLL RDADDLQKRL AVYQAGAREG AERGLSAIRE RLGPLVEQGR VRAATVGSLA GQPLQERAQA WGERLRARME EMGSRTRDRL DEVKEQVAEV RAKLEEQAQQ IRLQAEAFQA RLKSWFEPLV EDMQRQWAGL VEKVQAAVGT SAAPVPSDNH
- 产品特性
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Purified recombinant Human ApoE4 protein
Expression System: E.coli - 纯度
- > 90 % pure
- 内毒素水平
- < 0.1 ng per µg(1 EU/µg).
- Top Product
- Discover our top product APOE 蛋白
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstitute in water to a concentration of 0.1 - 1.0 mg/mL.
- 缓冲液
- Lyophilized from 20 mM Na3PO4, pH 7.8.
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- 抗原
- APOE (Apolipoprotein E (APOE))
- 别名
- ApoE4 (APOE 产品)
- 背景
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ApoE4 is the high risk variant of the APOE gene, the gene most associated with increased risk for late-onset Alzheimer's disease. Wikipedia shows that it is not a direct determinant of the disease - at least a third of patients with Alzheimer's disease are ApoE4 negative and some ApoE4 homozygotes never develop the disease. Yet those with ApoE4/ApoE4 have ~20x risk of developing Alzheimer's.
Alternative Names: Apo E4 protein, Apo-A4 protein, ApoE-4, ApoE 4 protein, ApoE-4 protein, Apolipoprotein E4 protein, ApoE 4, ApoE4 - 分子量
- 34.4 kDa
- 途径
- Regulation of Cell Size, Lipid Metabolism
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