ARTN 蛋白
Quick Overview for ARTN 蛋白 (ABIN935222)
抗原
See all ARTN 蛋白蛋白类型
生物活性
宿主
资源
纯度
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序列
- AGGPGSRARA AGARGCRLRS QLVPVRALGL GHRSDELVRF RFCSGSCRRA RSPHDLSLAS LLGAGALRPP PGSRPVSQPC CRPTRYEAVS FMDVNSTWRT VDRLSATACG CLG
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产品特性
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Purified recombinant Human Artemin protein
Expression System: E.coli
Bioactivity: Determined by it's ability to promote survival and neurite outgrowth and dorsal root ganglion neurons. -
纯化方法
- Heat shock method
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内毒素水平
- < 0.1 ng per µg (1 EU/µg).
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Artemin (ARTN) (AA 112-224) protein (Fc Tag)
ARTN 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Artemin (ARTN) (AA 108-220) protein (Fc Tag)ARTN 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Artemin (ARTN) (AA 108-220) protein (His tag)ARTN 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Artemin (ARTN) (AA 1-228) protein (GST tag)ARTN 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- Supplied as a lyophilized powder.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- ARTN (Artemin (ARTN))
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别名
- Artemin
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背景
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Artemin is a disulfide-linked homodimeric neurotrophic factor structurally related to GDNF, Artemin, Neurturin and Persephin. These proteins belong to the cysteine-knot superfamily of growth factors that assume stable dimeric protein structures. Artemin, GDNF, Persephin and Neurturin all signal through a multicomponent receptor system, composed of RET (receptor tyrosine kinase) and one of the four GFRalpha (alpha1-alpha4) receptors. Artemin prefers the receptor GFRalpha3-RET, but will use other receptors as an alternative. Artemin supports the survival of all peripheral ganglia such as sympathetic, neural crest and placodally derived sensory neurons, and dompaminergic midbrain neurons.
Alternative Names: EVN protein, Enovin protein, ART protein, Neublastin protein , ARTN protein, NBN protein -
分子量
- 24.4 kDa
抗原
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