CNTF Protein (AA 1-200)
Quick Overview for CNTF Protein (AA 1-200) (ABIN935113)
抗原
See all CNTF 蛋白蛋白类型
宿主
资源
应用范围
纯度
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产品特性
- AA 1-200
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序列
- MAFTEHSPLT PHRRDLCSRS IWLARKIRSD LTALTESYVK HQGLNKNINL DSADGMPVAS TDQWSELTEA ERLQENLQAY RTFHVLLARL LEDQQVHFTP TEGDFHQAIH TLLLQVAAFA YQIEELMILL EYKIPRNEAD GMPINVGDGG LFEKKLWGLK VLQELSQWTV RSIHDLRFIS SHQTGIPARG SHYIANNKKM
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产品特性
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Purified recombinant CNTF protein
Expression System: E.coli
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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实验流程
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CNTF protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Supplied as a liquid in 20 mM Tris-HCl buffer, pH 8.0, with 0 mM DTT, and 10 % glycerol.
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储存液
- Dithiothreitol (DTT)
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注意事项
- This product contains Dithiothreitol: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C for short term storage. Aliquot and store at -20 °C or -70 °C for long term storage.
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- CNTF (Ciliary Neurotrophic Factor (CNTF))
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别名
- CNTF
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背景
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CNTF (Ciliary neurotrophic factor) is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. This protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. CNTF protein is structurally related to leukemia inhibitory factor (LIF), interleukin-6 (IL-6), interleukin-11 (IL-11) and oncostatin M (OSM). It is localized in the cell nucleus subsequent to receptor binding. Recombinant human CNTF protein was expressed in E.coli and purified by using conventional chromatography techniques.
Alternative Names: Ciliary neurotrophic factor protein -
分子量
- 22.9 kDa
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途径
- JAK/STAT Signaling
抗原
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