TCL1A Protein (AA 1-114)
Quick Overview for TCL1A Protein (AA 1-114) (ABIN935060)
抗原
See all TCL1A 蛋白蛋白类型
宿主
资源
应用范围
纯度
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产品特性
- AA 1-114
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序列
- MAECPTLGEA VTDHPDRLWA WEKFVYLDEK QHAWLPLTIE IKDRLQLRVL LRREDVVLGR PMTPTQIGPS LLPIMWQLYP DGRYRSSDSS FWRLVYHIKI DGVEDMLLEL LPDD
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产品特性
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Purified recombinant Human TCL1 A protein
Expression System: E.coli
Molecular weight on SDS-PAGE will appear higher.
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应用备注
- TCL1A protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Supplied as a liquid in 50 mM Tris-HCl buffer, pH 7.5, containing 10 % glycerol.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- RT/-20 °C
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储存方法
- Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.
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- TCL1A (T-Cell Leukemia/lymphoma 1A (TCL1A))
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别名
- TCL1A
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背景
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TCL1A, also known as T-cell leukemia/lymphoma 1A, is a protein with a suggested role in intracellular regulation of T cell signaling. TCL1A binds to the pleckstrin homology domain of Akt (protein kinase B) family proteins, which facilitates Akt dimerization and activity. By increasing Akt activity TCL1A may enhance the serine/threonine phosphorylation of major Akt signaling substrates, such as Ikk complex, mTOR, BAD, p70S6 kinase, FOXO transcription factors, and GSK3b. These substrates regulate cellular differentiation, growth, survival, and metabolism. Recombinant TCL1A protein was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names: TCL 1 protein protein, T cell leukemia 1 protein, TCLA-1 protein, TCL1A, TCLA 1, TCL-1 protein, TCL1A protein, TCL1 oncogene protein, P14 TCL1 protein protein, protein p14TCL1 protein, TCL1 PEN protein, TCLA 1 protein, Oncogene TCL1 protein, T-cell leukemia/lymphoma 1A anti TCL1A protein, T cell lymphoma 1A protein, TCL1A., TCL1 protein, T cell lymphoma 1 protein, P14 TCL1 protein, TCLA-1 -
分子量
- 13.4 kDa (114 AA)
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途径
- Stem Cell Maintenance
抗原
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