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TCL1A Protein (AA 1-114)

This Recombinant TCL1A protein is expressed in Escherichia coli (E. coli).
产品编号 ABIN935060
发货至: 中国

Quick Overview for TCL1A Protein (AA 1-114) (ABIN935060)

抗原

See all TCL1A 蛋白
TCL1A (T-Cell Leukemia/lymphoma 1A (TCL1A))

蛋白类型

Recombinant

宿主

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资源

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大肠杆菌(E. Coli)

应用范围

SDS-PAGE (SDS)

纯度

> 90 % pure
  • 产品特性

    AA 1-114

    序列

    MAECPTLGEA VTDHPDRLWA WEKFVYLDEK QHAWLPLTIE IKDRLQLRVL LRREDVVLGR PMTPTQIGPS LLPIMWQLYP DGRYRSSDSS FWRLVYHIKI DGVEDMLLEL LPDD

    产品特性

    Purified recombinant Human TCL1 A protein
    Expression System: E.coli
    Molecular weight on SDS-PAGE will appear higher.
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  • 应用备注

    TCL1A protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Supplied as a liquid in 50 mM Tris-HCl buffer, pH 7.5, containing 10 % glycerol.

    注意事项

    Avoid repeated freeze/thaw cycles.

    储存条件

    RT/-20 °C

    储存方法

    Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.
  • 抗原

    TCL1A (T-Cell Leukemia/lymphoma 1A (TCL1A))

    别名

    TCL1A

    背景

    TCL1A, also known as T-cell leukemia/lymphoma 1A, is a protein with a suggested role in intracellular regulation of T cell signaling. TCL1A binds to the pleckstrin homology domain of Akt (protein kinase B) family proteins, which facilitates Akt dimerization and activity. By increasing Akt activity TCL1A may enhance the serine/threonine phosphorylation of major Akt signaling substrates, such as Ikk complex, mTOR, BAD, p70S6 kinase, FOXO transcription factors, and GSK3b. These substrates regulate cellular differentiation, growth, survival, and metabolism. Recombinant TCL1A protein was expressed in E. coli and purified by using conventional chromatography techniques.
    Alternative Names: TCL 1 protein protein, T cell leukemia 1 protein, TCLA-1 protein, TCL1A, TCLA 1, TCL-1 protein, TCL1A protein, TCL1 oncogene protein, P14 TCL1 protein protein, protein p14TCL1 protein, TCL1 PEN protein, TCLA 1 protein, Oncogene TCL1 protein, T-cell leukemia/lymphoma 1A anti TCL1A protein, T cell lymphoma 1A protein, TCL1A., TCL1 protein, T cell lymphoma 1 protein, P14 TCL1 protein, TCLA-1

    分子量

    13.4 kDa (114 AA)

    途径

    Stem Cell Maintenance
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