(3 references)-
- 抗原 See all alpha-Thrombin products
- alpha-Thrombin
- 蛋白类型
- Native
- 生物活性
- Active
-
宿主
- 人
-
资源
- Human
- 产品特性
-
Purified native Human alpha Thrombin protein
Bioactivity: 4493 units/mg protein- Specific activity is determined by fibrinogen clotting assay relative to human NIH standard thrombin.
Protein Source: Human serum/plasma - 纯度
- > 95 % pure
-
-
- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- Supplied as a liquid with 50 % Glycerol/H2 O (vol/vol).
- 注意事项
- Donor samples were tested and found to be negative for anti-HIV-1/2, HIV-1 antigen(s), HBsAg, STS, anti-HCV, anti-HBcore and anti-HTLV I & II. Nonetheless caution should be used when handling this material as there is a margin of error in all tests.
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- Aliquot and store at -20 °C.
-
-
: "Semisynthetic Approach toward Biologically Active Derivatives of Phenylspirodrimanes from S. chartarum." in: ACS omega, Vol. 7, Issue 49, pp. 45215-45230, (2022) (PubMed).
: "Pyrazole-Based Thrombin Inhibitors with a Serine-Trapping Mechanism of Action: Synthesis and Biological Activity." in: Pharmaceuticals (Basel, Switzerland), Vol. 15, Issue 11, (2022) (PubMed).
: "Microscale Parallel Synthesis of Acylated Aminotriazoles Enabling the Development of Factor XIIa and Thrombin Inhibitors." in: ChemMedChem, Vol. 16, Issue 24, pp. 3672-3690, (2022) (PubMed).
-
: "Semisynthetic Approach toward Biologically Active Derivatives of Phenylspirodrimanes from S. chartarum." in: ACS omega, Vol. 7, Issue 49, pp. 45215-45230, (2022) (PubMed).
-
- 抗原
- alpha-Thrombin
- 别名
- alpha Thrombin (alpha-Thrombin 产品)
- 别名
- PT Protein, RPRGL2 Protein, THPH1 Protein, coagulation factor II, thrombin Protein, F2 Protein
- 背景
-
Alpha-thrombin is a highly specific serine protease generated by proteolytic activation of the zymogen prothrombin. During coagulation, thrombin cleaves fibrinogen to form fibrin, leading to the ultimate step in coagulation, the formation of a fibrin clot. Thrombin is also responsible for feedback activation of the procofactors factor V and factor VIII.
Description: Human serum/plasma.
Alternative Names: Thrombin alpha protein - 分子量
- 36.7 kDa
-
You are here:
