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Troponin I Protein (TNNI)

This Native Troponin I protein is expressed in Human and has been mentioned in 1 publication.
产品编号 ABIN934718
发货至: 中国

Quick Overview for Troponin I Protein (TNNI) (ABIN934718)

抗原

See all Troponin I (TNNI) 蛋白
Troponin I (TNNI)

蛋白类型

Native

宿主

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资源

  • 1
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Human

纯度

> 99 % pure
  • 产品特性

    Purified native Human Troponin I protein (Cardiac)
    Protein Source: Human cardiac tissue
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  • 应用备注

    Each Investigator should determine their own optimal working dilution for specific applications.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Supplied as a liquid in 8 M Urea buffer with 30 mM NaCl, 50 mM Tris. HCl, 15 mM beta-mercaptoethanol, 1 mM EGTA, pH 8.0

    注意事项

    Donor samples were tested and found to be negative for HBsAg, Anti-HIV-1/HIV-2, & HCV. Nonetheless caution should be used when handling this material as there is a margin of error in all tests.

    注意事项

    Avoid repeated freeze/thaw cycles.

    储存条件

    -20 °C/-80 °C

    储存方法

    Store at -20 °C to -70 °C,
  • Mulvaney, Cole, Kniller, Malito, Tamanaha, Rife, Stanton, Whitman: "Rapid, femtomolar bioassays in complex matrices combining microfluidics and magnetoelectronics." in: Biosensors & bioelectronics, Vol. 23, Issue 2, pp. 191-200, (2007) (PubMed).

  • 抗原

    Troponin I (TNNI)

    别名

    Troponin I

    背景

    Troponin I is a part of the troponin complex. It binds to actin in thin myofilaments to hold the actin-tropomyosin complex in place. Because of it myosin cannot bind actin in relaxed muscle. When calcium binds to the Troponin C it causes conformational changes which lead to dislocation of troponin I and finally tropomyosin leaves the binding site for myosin on actin leading to contraction of muscle. The letter I is given due to its inhibitory character.
    Description: Human cardiac tissue.
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