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IGF2 蛋白

IGF2 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 98 % pure Active
产品编号 ABIN934624
发货至: 中国
  • 抗原 See all IGF2 蛋白
    IGF2 (Insulin-Like Growth Factor 2 (IGF2))
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 17
    • 3
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    • 3
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    • 3
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    资源
    • 29
    • 8
    • 3
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    • 1
    大肠杆菌(E. Coli)
    序列
    AYRPSETLCG GELVDTLQFV CGDRGFYFSR PASRVSRRSR GIVEECCFRS CDLALLETYC ATPAKSE
    产品特性
    Purified recombinant Human IGF2 protein
    Expression System: E.coli
    Bioactivity: The ED50 was determined by a cell proliferation assay using FDC-P1 cells is ? 2.0 ng/mL, corresponding to a specific activity of ? 5 x 10^5 units/mg.
    纯度
    > 98 % pure
    内毒素水平
    < 0.1 ng per µg (1 EU/µg).
    Top Product
    Discover our top product IGF2 蛋白
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute in water to a concentration of 0.1 - 1.0 mg/mL.
    缓冲液
    Supplied as a lyophilized powder.
    注意事项
    Avoid repeated freeze/thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
  • 抗原
    IGF2 (Insulin-Like Growth Factor 2 (IGF2))
    别名
    IGF2 (IGF2 产品)
    背景
    The IGFs are mitogenic polypeptide growth factors that stimulate the proliferation and survival of various cell types including muscle, bone, and cartilage tissue in vitro. IGFs are predominantly produced by the liver, although a variety of tissues produce the IGFs at distinctive times. The IGFs belong to the Insulin gene family, which also contains insulin and relaxin. The IGFs are similar by structure and function to insulin, but have a much higher growth-promoting activity than insulin. IGF-II expression is influenced by placenta lactogen, while IGF-I expression is regulated by growth hormone. Both IGF-I and IGF-II signal through the tyrosine kinase type I receptor (IGF-IR), but, IGF-II can also signal through the IGF-II/Mannose-6-phosphate receptor. Mature IGFs are generated by proteolytic processing of inactive precursor proteins, which contain N-terminal and C-terminal propeptide regions.
    Alternative Names: IGF 2 protein, Somatamedin A protein, Insulin-like Growth Factor-2 protein, IGF-2 protein, IGF2, IGF 2, IGF-2
    途径
    Hormone Activity, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Carbohydrate Metabolic Process, Activated T Cell Proliferation
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