IGF2 蛋白
Quick Overview for IGF2 蛋白 (ABIN934624)
抗原
See all IGF2 蛋白蛋白类型
生物活性
宿主
资源
纯度
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序列
- AYRPSETLCG GELVDTLQFV CGDRGFYFSR PASRVSRRSR GIVEECCFRS CDLALLETYC ATPAKSE
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产品特性
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Purified recombinant Human IGF2 protein
Expression System: E.coli
Bioactivity: The ED50 was determined by a cell proliferation assay using FDC-P1 cells is ? 2.0 ng/mL, corresponding to a specific activity of ? 5 x 10^5 units/mg. -
内毒素水平
- < 0.1 ng per µg (1 EU/µg).
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Insulin-Like Growth Factor 2 (IGF2) (AA 1-113) protein (GST tag)
IGF2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Insulin-Like Growth Factor 2 (IGF2) (AA 1-180) protein (GST tag)IGF2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Insulin-Like Growth Factor 2 (IGF2) proteinIGF2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant 97,00% SDS
Insulin-Like Growth Factor 2 (IGF2) (AA 25-91) (Active) protein (Fc Tag)IGF2 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Insulin-Like Growth Factor 2 (IGF2) proteinIGF2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant 97,00% SDS
Insulin-Like Growth Factor 2 (IGF2) (AA 30-180), (partial) protein (GST tag)IGF2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant 90 % SDS, ELISA
Insulin-Like Growth Factor 2 (IGF2) (AA 25-91) (Active) protein (AVI tag,Fc Tag,Biotin)IGF2 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Func Active
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstitute in water to a concentration of 0.1 - 1.0 mg/mL.
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缓冲液
- Supplied as a lyophilized powder.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- IGF2 (Insulin-Like Growth Factor 2 (IGF2))
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别名
- IGF2
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背景
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The IGFs are mitogenic polypeptide growth factors that stimulate the proliferation and survival of various cell types including muscle, bone, and cartilage tissue in vitro. IGFs are predominantly produced by the liver, although a variety of tissues produce the IGFs at distinctive times. The IGFs belong to the Insulin gene family, which also contains insulin and relaxin. The IGFs are similar by structure and function to insulin, but have a much higher growth-promoting activity than insulin. IGF-II expression is influenced by placenta lactogen, while IGF-I expression is regulated by growth hormone. Both IGF-I and IGF-II signal through the tyrosine kinase type I receptor (IGF-IR), but, IGF-II can also signal through the IGF-II/Mannose-6-phosphate receptor. Mature IGFs are generated by proteolytic processing of inactive precursor proteins, which contain N-terminal and C-terminal propeptide regions.
Alternative Names: IGF 2 protein, Somatamedin A protein, Insulin-like Growth Factor-2 protein, IGF-2 protein, IGF2, IGF 2, IGF-2 -
途径
- Hormone Activity, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Carbohydrate Metabolic Process, Activated T Cell Proliferation
抗原
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