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IL16 蛋白

This Recombinant IL16 protein is expressed in 大肠杆菌(E. Coli) and has been mentioned in 1 publication.
产品编号 ABIN934622
发货至: 中国

Quick Overview for IL16 蛋白 (ABIN934622)

抗原

See all IL16 蛋白
IL16 (Interleukin 16 (IL16))

蛋白类型

Recombinant

生物活性

Active

宿主

  • 17
  • 9
  • 2
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  • 2
  • 1
  • 1

资源

  • 28
  • 3
  • 2
  • 1
大肠杆菌(E. Coli)

纯度

> 97 % pure
  • 序列

    MPDLNSSTDS AASASAASDV SVESTAEATV CTVTLEKMSA GLGFSLEGGK GSLHGDKPLT INRIFKGAAS EQSETVQPGD EILQLGGTAM QGLTRFEAWN IIKALPDGPV TIVIRRKSLQ SKETTAAGDS

    产品特性

    Purified recombinant Human IL16 protein
    Expression System: E.coli
    Bioactivity: Determined by its ability to chemoattract human CD4+ T lymphoytes using a concentration range of 1.0-100.0 ng/mL.

    内毒素水平

    < 0.1 ng per µg (1 EU/µg).
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    表达系统 HEK-293 Cells
    Conjugate His tag
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    价格从 172,528.32 ¥

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  • 应用备注

    Each Investigator should determine their own optimal working dilution for specific applications.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Reconstitute in water to a concentration of 0.1-1.0 mg/mL.

    缓冲液

    Lyophilized from 5 mM Na3PO4, pH 7.6.

    注意事项

    Avoid repeated freeze/thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
  • Liu, Mills, Dixon, Vennarini, Cunningham, Del Vecchio, Das, Glass: "IL-16 signaling specifically induces STAT6 activation through CD4." in: Cytokine, Vol. 38, Issue 3, pp. 145-50, (2007) (PubMed).

  • 抗原

    IL16 (Interleukin 16 (IL16))

    别名

    IL16

    背景

    IL16 is a CD8+ T cell-derived cytokine that induces chemotaxis of CD4+ T cells and CD4+ monocytes and eosinophils. Analysis by gel filtration suggests that, under physiological conditions, hIL16 exists predominantly as a noncovalently linked multimer, but that some IL16 may exist as a monomer. However, only the multimeric form appears to possess chemotactic activity, suggesting that receptor cross-linking may be required for activity. IL16 also induces expression of IL2 receptor (IL2R) and MHC class II molecules on CD4 + T cells. Human and Mouse IL16 show significant cross-species reactivity.
    Alternative Names: IL-16 protein, IL16, IL-16 protein, Interleukin 16 protein, IL 16, Lymphocyte Chemoattractant Factor protein, IL 16 protein, LCF protein, IL-16

    分子量

    13.5 kDa
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