宿主: 人
宿主: 大肠杆菌(E. Coli)
Recombinant
SDS, ELISA, HPLC
Active
应用备注
Each Investigator should determine their own optimal working dilution for specific applications.
限制
仅限研究用
状态
Lyophilized
缓冲液
Supplied as a lyophilized powder purified by HPLC, tyrosine residue.
注意事项
Avoid repeated freeze/thaw cycles.
储存条件
-20 °C
储存方法
Aliquot and store at -20 °C.
抗原
C-Peptide
别名
C Peptide
背景
Proinsulin C-peptide was first described in 1967 in connection with the discovery of the insulin biosynthesis. It serves as an important linker between the A- and the B- chains of insulin and facilitates the efficient assembly, folding, and processing of insulin in the endoplasmic reticulum. Equimolar amounts of C-peptide and insulin are then stored in secretory granules of the pancreatic beta cells and both are eventually released to the portal circulation. Initially, the sole interest in C-peptide was as a marker of insulin secretion and has as such been of great value in furthering the understanding of the pathophysiology of type 1 and type 2 diabetes. The first documented use of the C-peptide test was in 1972. During the past decade, however, C-peptide has been found to be a bioactive peptide in its own right, with effects on microvascular blood flow and tissue health. Description: Human (full length synthetic C-peptide) Tyr-C-Peptide. Alternative Names: Proinsulin connecting peptide, C-Peptide protein