IL-2 蛋白
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北京 101111
Quick Overview for IL-2 蛋白 (ABIN8057021)
抗原
See all IL-2 (IL2) 蛋白蛋白类型
生物活性
宿主
资源
应用范围
纯度
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原理
- Recombinant Human Interleukin-2/IL-2 Protein (active)
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序列
- Ala 21-Thr 153
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过滤
- 0.2 μm filtered
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内毒素水平
- ≤0.01 EU per μg by the LAL method.
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Biological Activity Comment
- Human IL-2 Protein, Tag Free stimulates proliferation of CTLL-2 cells. The specific activity of Human IL-2 Protein, Tag Free is > 0.60 x 10^7 IU/mg, which is calibrated against human IL-2 WHO International Standard.
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4 with trehalose as protectant.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- IL-2 (IL2) (Interleukin 2 (IL2))
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别名
- Interleukin-2
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背景
- Interleukin-2,IL-2,T-Cell Growth Factor,TCGF,Aldesleukin,Interleukin-2(IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system,belongs to the IL-2 family. It is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages and oligodendrocytes.
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分子量
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Calculated MW: 15.4 kDa
Observed MW: 14-22 kDa
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UniProt
- P60568-1
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途径
- JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
抗原
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