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IL-2 蛋白

This Recombinant IL-2 protein is expressed in HEK-293 Cells.
产品编号 ABIN8057021
发货至: 中国
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Quick Overview for IL-2 蛋白 (ABIN8057021)

抗原

See all IL-2 (IL2) 蛋白
IL-2 (IL2) (Interleukin 2 (IL2))

蛋白类型

Recombinant

生物活性

Active

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HEK-293 Cells

应用范围

Cell Culture (CC)

纯度

> 95 % as determined by reducing SDS-PAGE.
  • 原理

    Recombinant Human Interleukin-2/IL-2 Protein (active)

    序列

    Ala 21-Thr 153

    过滤

    0.2 μm filtered

    内毒素水平

    ≤0.01 EU per μg by the LAL method.

    Biological Activity Comment

    Human IL-2 Protein, Tag Free stimulates proliferation of CTLL-2 cells. The specific activity of Human IL-2 Protein, Tag Free is > 0.60 x 10^7 IU/mg, which is calibrated against human IL-2 WHO International Standard.
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  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4 with trehalose as protectant.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    有效期

    12 months
  • 抗原

    IL-2 (IL2) (Interleukin 2 (IL2))

    别名

    Interleukin-2

    背景

    Interleukin-2,IL-2,T-Cell Growth Factor,TCGF,Aldesleukin,Interleukin-2(IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system,belongs to the IL-2 family. It is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages and oligodendrocytes.

    分子量

    Calculated MW: 15.4 kDa

    Observed MW: 14-22 kDa

    UniProt

    P60568-1

    途径

    JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
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