TET1 Protein (AA 1634-1986, AA 2601-2708)
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Quick Overview for TET1 Protein (AA 1634-1986, AA 2601-2708) (ABIN7939796)
抗原
See all TET1 蛋白蛋白类型
宿主
资源
应用范围
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产品特性
- AA 1634-1986, AA 2601-2708
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原理
- Recombinant DmTet (1634-1986, 2601-2708) protein
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Tet Methylcytosine Dioxygenase 1 (TET1) (AA 2038-2136) protein (GST tag)
TET1 宿主: 人 宿主: 小麦胚 Recombinant WB, AP, AA, ELISA
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Recombinant DmTet (1634-1986 and 2601-2708) protein is supplied in 25 mM Tris pH 7.4, 300 mM NaCl, 10 % glycerol, and 0.5 mM TCEP.
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注意事项
- Avoid repeated freeze/thaw cycles,keep on ice when not in storage
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储存条件
- -80 °C
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储存方法
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
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- TET1 (Tet Methylcytosine Dioxygenase 1 (TET1))
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别名
- DmTet
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背景
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Protein Background: Ten Eleven Translocation (TET) family proteins are cytosine oxygenases that catalyze the conversion of 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC). 5hmC can be further oxidized into 5-formylcytosine (5fC) and 5-carboxylcytosine (5caC) by TET proteins. Methylation at the C5 position of cytosine is an epigenetic modification of the mammalian genome that plays an important role in transcriptional regulation. TET proteins are responsible for initiating the enzymatic deamination process leading to cytosine demethylation.
Short Description: Recombinant DmTet (1634-1986 and 2601-2708) protein was expressed in E. colicells as the Protein fragment (accession number NP_001246581.1) with an N-terminal 6xHis tag. The molecular weight of DmTet (1634-1986 and 2601-2708) is 53.68 kDa.
Aliases: Drosophila melanogaster Tet-like protein
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途径
- Stem Cell Maintenance, Warburg Effect
抗原
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