YTHDC2 Protein (full length)
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Quick Overview for YTHDC2 Protein (full length) (ABIN7939765)
抗原
蛋白类型
宿主
资源
应用范围
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产品特性
- full length
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原理
- Recombinant YTHDC2 protein
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产品特性
- Recombinant YTHDC2 protein was expressed in a baculovirus expression system as the full-length protein (accession number NP_073739.3) with an N-terminal Flag tag. The molecular weight of the protein is 161.5 kDa. It is suitable for use in binding assays, inhibitor screening, and selectivity profiling.
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Recombinant YTHDC2 protein is supplied in 25 mM HEPES-NaOH pH 7.5, 300 mM NaCl, 10 % glycerol, 0.04 % Triton X-100, and 0.5 mM TCEP.
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注意事项
- Avoid repeated freeze/thaw cycles,keep on ice when not in storage
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储存条件
- -80 °C
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储存方法
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
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- YTHDC2 (YTH Domain Containing 2 (YTHDC2))
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别名
- YTHDC2
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背景
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Protein Background: YTHDC2 (YTH Domain Containing 2), is a member of the DEAH (Asp-Glu-Ala-His) subfamily of proteins, part of the DEAD (Asp-Glu-Ala-Asp) box family of RNA helicases. It specifically recognizes and binds to N6-methyladenosine (m6A), a common modified RNA nucleotide that is enriched in the stop codons and 3' UTRs of eukaryotic mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability. YTHDC2 may be associated with susceptibility to pancreatic cancer in human patients, and knockdown of this gene resulted in reduced proliferation in a human liver cancer cell line.
Short Description: Recombinant YTHDC2 protein was expressed in a baculovirus expression system as the full length protein (accession number NP_073739.3) with an N-terminal Flag tag. The molecular weight of the protein is 161.5 kDa.
Aliases: YTH Domain Containing 2
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分子量
- 161.5 kDa
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NCBI登录号
- NP_073739
抗原
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