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UBA7 蛋白

This Recombinant UBA7 protein is expressed in Baculovirus infected Insect Cells.
产品编号 ABIN7939725
发货至: 中国
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Quick Overview for UBA7 蛋白 (ABIN7939725)

抗原

See all UBA7 蛋白
UBA7 (Ubiquitin-Like Modifier Activating Enzyme 7 (UBA7))

蛋白类型

Recombinant

宿主

资源

  • 2
  • 2
  • 1
  • 1
  • 1
Baculovirus infected Insect Cells

应用范围

Activity Assay (AcA), Functional Studies (Func), Screening Assay (ScA)
  • 原理

    Recombinant UBA7 (UBE1L) protein
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    表达系统
    Conjugate
    Origin
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    表达系统 HEK-293 Cells
    Conjugate His tag
    Origin Human
    价格从 116,946.14 ¥
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    Conjugate Strep Tag
    Origin Human
    价格从 145,985.55 ¥

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  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Recombinant UBA7 (UBE1L) protein is supplied in 25 mM HEPES pH 7.5, 300 mM NaCl, 20 % glycerol, 0.04 % Triton X-100, 0.5 mM TCEP.

    注意事项

    Avoid repeated freeze/thaw cycles,keep on ice when not in storage

    储存条件

    -80 °C

    储存方法

    Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
  • 抗原

    UBA7 (Ubiquitin-Like Modifier Activating Enzyme 7 (UBA7))

    别名

    UBA7

    背景

    Protein Background: UBA7 is an E1-activating enzyme that catalyzes the covalent conjugation of the ubiquitin-like protein product of ISG15 to additional interferon stimulated proteins (ISGs) as well as other cellular proteins such as P53 in a process termed protein ISGylation. Plays an essential role in antiviral immunity together with ISG15 by restricting the replication of many viruses including rabies virus, influenza virus, sindbis virus, rotavirus or human cytomegalovirus. For example, ISG15 modification of influenza A protein NS1 disrupts the association of the NS1 with importin-alpha leading to NS1 nuclear import inhibition. ISGylation of human cytomegalovirs protein UL26 regulates its stability and inhibits its activities to suppress NF-kappa-B signaling.

    Short Description: Recombinant UBA7 (UBE1L) protein was expressed in a baculovirus expression system as the full length protein (accession number NP_003326.2) with an N-terminal FLAG tag. The molecular weight of UBA7 is 112.96 kDa.

    Aliases: UBE2, D8, UBA1B, UBE1L, Ubiquitin Like Modifier Activating Enzyme

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