UBA7 蛋白
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北京 101111
Quick Overview for UBA7 蛋白 (ABIN7939725)
抗原
See all UBA7 蛋白蛋白类型
宿主
资源
应用范围
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原理
- Recombinant UBA7 (UBE1L) protein
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!探索我们的预定义定制蛋白和定制蛋白服务!Product表达系统ConjugateOrigin价格从表达系统 HEK-293 CellsConjugate His tagOrigin Human价格从 116,946.14 ¥表达系统 Cell-free protein synthesis (CFPS)Conjugate Strep TagOrigin Human价格从 145,985.55 ¥您的项目需要进一步定制吗?联系我们,了解我们的定制蛋白解决方案
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Recombinant UBA7 (UBE1L) protein is supplied in 25 mM HEPES pH 7.5, 300 mM NaCl, 20 % glycerol, 0.04 % Triton X-100, 0.5 mM TCEP.
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注意事项
- Avoid repeated freeze/thaw cycles,keep on ice when not in storage
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储存条件
- -80 °C
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储存方法
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
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- UBA7 (Ubiquitin-Like Modifier Activating Enzyme 7 (UBA7))
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别名
- UBA7
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背景
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Protein Background: UBA7 is an E1-activating enzyme that catalyzes the covalent conjugation of the ubiquitin-like protein product of ISG15 to additional interferon stimulated proteins (ISGs) as well as other cellular proteins such as P53 in a process termed protein ISGylation. Plays an essential role in antiviral immunity together with ISG15 by restricting the replication of many viruses including rabies virus, influenza virus, sindbis virus, rotavirus or human cytomegalovirus. For example, ISG15 modification of influenza A protein NS1 disrupts the association of the NS1 with importin-alpha leading to NS1 nuclear import inhibition. ISGylation of human cytomegalovirs protein UL26 regulates its stability and inhibits its activities to suppress NF-kappa-B signaling.
Short Description: Recombinant UBA7 (UBE1L) protein was expressed in a baculovirus expression system as the full length protein (accession number NP_003326.2) with an N-terminal FLAG tag. The molecular weight of UBA7 is 112.96 kDa.
Aliases: UBE2, D8, UBA1B, UBE1L, Ubiquitin Like Modifier Activating Enzyme
抗原
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