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UBE2D2 蛋白

This Recombinant UBE2D2 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN7939683
发货至: 中国
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Quick Overview for UBE2D2 蛋白 (ABIN7939683)

抗原

See all UBE2D2 蛋白
UBE2D2 (Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2))

蛋白类型

Recombinant

宿主

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资源

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大肠杆菌(E. Coli)

应用范围

Activity Assay (AcA), Functional Studies (Func), Screening Assay (ScA)
  • 原理

    Recombinant UBE2D2 protein
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    Product
    表达系统
    Conjugate
    Origin
    价格从
    表达系统 HEK-293 Cells
    Conjugate His tag
    Origin Human
    价格从 116,946.14 ¥
    表达系统 Cell-free protein synthesis (CFPS)
    Conjugate Strep Tag
    Origin Human
    价格从 145,985.55 ¥

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  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Recombinant UBE2D2 protein is supplied in 25 mM Tris 7.4, 300 mM NaCl, 20 % glycerol, 0.5 mM TCEP.

    注意事项

    Avoid repeated freeze/thaw cycles,keep on ice when not in storage

    储存条件

    -80 °C

    储存方法

    Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
  • 抗原

    UBE2D2 (Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2))

    别名

    UBE2D2

    背景

    Protein Background: UBE2D2 (Ubiquitin-conjugating enzyme E2 D2) also known as E2(17) KB2, PUBC1, UBC4, UBC4/5, UBCH4 and UBCH5B. UBE2D2 is a member of the E2 ubiquitin-conjugating enzyme family which is required for post replicative DNA damage repair and plays an important role in various cellular processes. UBE2D2 can accept ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6 AP-induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and autoubiquitination of STUB1 and TRAF6. Involved in the signal-induced conjugation and subsequent degradation of NFKBIA, FBXW2 mediated GCM1 ubiquitination and degradation, MDM2-dependent degradation of p53/TP53 and the activation of MAVS in the mitochondria by RIGI in response to viral infection.

    Short Description: Recombinant UBE2D2 protein that includes full length of human UBE2D2 protein (accession number NP_003330.1) was expressed in E. coli and contains an N-terminal His tag with a molecular weight of 18.90 kDa. The purity of the protein is ≥ 70 % by SDS-PAGE.

    Aliases: Ubiquitin conjugating enzyme E2 D2, E2(17)KB2, PUBC1, UBC4, UBC4/5, UBCH4, UBCH5B

    途径

    Activation of Innate immune Response, Toll-Like Receptors Cascades
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