UBE2B 蛋白
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北京 101111
Quick Overview for UBE2B 蛋白 (ABIN7939676)
抗原
See all UBE2B 蛋白蛋白类型
宿主
资源
应用范围
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原理
- Recombinant UBE2B protein
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!探索我们的预定义定制蛋白和定制蛋白服务！Product表达系统ConjugateOrigin价格从表达系统 HEK-293 CellsConjugate His tagOrigin Human价格从 116,946.14 ¥表达系统 Cell-free protein synthesis (CFPS)Conjugate Strep TagOrigin Human价格从 145,985.55 ¥您的项目需要进一步定制吗？联系我们，了解我们的定制蛋白解决方案
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Ubiquitin-Conjugating Enzyme E2B (UBE2B) (AA 1-152) protein (His tag)
custom-made UBE2B 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Ubiquitin-Conjugating Enzyme E2B (UBE2B) (AA 1-152) protein (GST tag)UBE2B 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Ubiquitin-Conjugating Enzyme E2B (UBE2B) (AA 1-152) protein (His tag)UBE2B 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
Ubiquitin-Conjugating Enzyme E2B (UBE2B) (AA 1-152) protein (His-IF2DI Tag)UBE2B 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. ELISA, WB
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Recombinant UBE2B protein is supplied in 25 mM Tris 8.0, 300 mM NaCl, 20 % glycerol, 0.5 mM TCEP.
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注意事项
- Avoid repeated freeze/thaw cycles,keep on ice when not in storage
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储存条件
- -80 °C
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储存方法
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
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- UBE2B (Ubiquitin-Conjugating Enzyme E2B (UBE2B))
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别名
- UBE2B
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背景
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Protein Background: UBE2B (Ubiquitin-conjugating enzyme E2 B) also known as E2-17 kDa, HHR6B, HR6B, RAD6B and UBC2. UBE2B is a member of the E2 ubiquitin-conjugating enzyme family which is required for post-replicative DNA damage repair and plays an important role in various cellular processes. UBE2B can accept ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In association with the E3 enzyme BRE1 (RNF20 and/or RNF40), it plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B at 'Lys-120' to form H2BK120ub1. H2BK120ub1 gives a specific tag for epigenetic transcriptional activation, elongation by RNA polymerase II, telomeric silencing, and is also a prerequisite for H3K4me and H3K79me formation. In vitro catalyzes 'Lys-11'-, as well as 'Lys-48'- and 'Lys-63'-linked polyubiquitination. Required for postreplication repair of UV-damaged DNA. Associates to the E3 ligase RAD18 to form the UBE2B-RAD18 ubiquitin ligase complex involved in mono-ubiquitination of DNA-associated PCNA on 'Lys-164'. May be involved in neurite outgrowth.
Short Description: Recombinant UBE2B protein that includes full length of human UBE2B protein (accession number NP_003328.1) was expressed in E. coli and contains an N-terminal His tag with a molecular weight of 19.48 kDa. The purity of the protein is ≥ 95 % by SDS-PAGE.
Aliases: Ubiquitin conjugating enzyme E2 B, E2-17 kDa, HHR6B, RAD6B, UBC2
抗原
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