UBE2V2 蛋白
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北京 101111
Quick Overview for UBE2V2 蛋白 (ABIN7939673)
抗原
See all UBE2V2 蛋白蛋白类型
宿主
资源
应用范围
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原理
- Recombinant UBE2V2 protein
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Ubiquitin-Conjugating Enzyme E2 Variant 2 (UBE2V2) (AA 1-145) protein (GST tag)
UBE2V2 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Ubiquitin-Conjugating Enzyme E2 Variant 2 (UBE2V2) (AA 2-145) protein (His-IF2DI Tag)UBE2V2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. ELISA, WB
Ubiquitin-Conjugating Enzyme E2 Variant 2 (UBE2V2) (AA 2-145) protein (His-SUMO Tag)UBE2V2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. SDS
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Recombinant UBE2V2 protein is supplied in 25 mM Tris 8.0, 300 mM NaCl, 20 % glycerol, 0.5 mM TCEP.
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注意事项
- Avoid repeated freeze/thaw cycles,keep on ice when not in storage
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储存条件
- -80 °C
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储存方法
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
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- UBE2V2 (Ubiquitin-Conjugating Enzyme E2 Variant 2 (UBE2V2))
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别名
- UBE2V2
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背景
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Protein Background: UBE2V2 (Ubiquitin-conjugating enzyme E2 variant 2)also known as DDVit-1, DDVIT1, EDAF-1, EDPF-1, EDPF1, MMS2, UEV-2 and UEV2. UBE2V2 is a member of the E2 ubiquitin-conjugating enzyme family which is required for post-replicative DNA damage repair and plays an important role in various cellular processes. UBE2V2 has no ubiquitin ligase activity on its own. The UBE2V2/UBE2N heterodimer catalyzes the synthesis of non-canonical polyubiquitin chains that are linked through 'Lys-63'. This type of poly-ubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage.
Short Description: Recombinant UBE2V2 protein that includes full length of human UBE2V2 protein (accession number NP_003341.1) was expressed in E. coli and contains an N-terminal His tag with a molecular weight of 18.53 kDa. The purity of the protein is ≥ 95 % by SDS-PAGE.
Aliases: Ubiquitin conjugating enzyme E2 variant 2, DDVit-1, DDVIT1, EDAF-1, EDPF-1, EDPF1, MMS2, UEV-2, UEV2
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途径
- Positive Regulation of Response to DNA Damage Stimulus
抗原
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