SSRP1 蛋白
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北京 101111
Quick Overview for SSRP1 蛋白 (ABIN7939614)
抗原
See all SSRP1 蛋白蛋白类型
宿主
资源
应用范围
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原理
- Recombinant FACT complex
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Structure Specific Recognition Protein 1 (SSRP1) (AA 1-709) protein (GST tag)
SSRP1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Structure Specific Recognition Protein 1 (SSRP1) protein (Myc-DYKDDDDK Tag)SSRP1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Recombinant FACT Complex is supplied in 25 mM HEPES pH 7.5, 300 mM NaCl, 20 % glycerol, 0.04 % Triton X-100, 0.5 mM TCEP.
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注意事项
- Avoid repeated freeze/thaw cycles,keep on ice when not in storage
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储存条件
- -80 °C
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储存方法
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
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- SSRP1 (Structure Specific Recognition Protein 1 (SSRP1))
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别名
- FACT
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背景
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Protein Background: The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II. The FACT complex is probably also involved in phosphorylation of 'Ser 392' of p53/TP53 via its association with CK2 (casein kinase II).
Short Description: Recombinant FACT Complex that includes full length human SUPT16H protein (accession number NP_009123.1) without any tag and full length human SSRP1 protein (accession number NP_003137.1) with an N-terminal FLAG tag was expressed in Hi5 cells. The molecular weights of SUPT16H and SSRP1 are 120 kDa and 82.2 kDa, respectively.
Aliases: FACT80, FACTp80, T160, Structure Specific Recognition Protein 1
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途径
- Chromatin Binding
抗原
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