SUMO1 蛋白
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北京 101111
Quick Overview for SUMO1 蛋白 (ABIN7939594)
抗原
See all SUMO1 蛋白蛋白类型
宿主
资源
应用范围
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原理
- Recombinant SUMO1 protein - biotinylated
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Small Ubiquitin Related Modifier Protein 1 (SUMO1) (AA 1-101) protein (GST tag)
SUMO1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Small Ubiquitin Related Modifier Protein 1 (SUMO1) (AA 1-97) proteinSUMO1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % pure SDS
Small Ubiquitin Related Modifier Protein 1 (SUMO1) (AA 2-97) protein (GST tag)SUMO1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. ELISA, WB
Small Ubiquitin Related Modifier Protein 1 (SUMO1) (Transcript Variant 2) proteinSUMO1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Small Ubiquitin Related Modifier Protein 1 (SUMO1) (AA 2-98) protein (His-SUMO Tag)SUMO1 宿主: Saccharomyces cerevisiae 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
Small Ubiquitin Related Modifier Protein 1 (SUMO1) (AA 2-98) protein (His tag)SUMO1 宿主: Saccharomyces cerevisiae 宿主: 酵母菌 Recombinant > 90 % SDS
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Recombinant SUMO1 protein - biotinylated is supplied in 25 mM Tris pH 8.0, 300 mM NaCl, 20 % glycerol, 0.5 mM TCEP.
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注意事项
- Avoid repeated freeze/thaw cycles,keep on ice when not in storage
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储存条件
- -80 °C
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储存方法
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
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- SUMO1 (Small Ubiquitin Related Modifier Protein 1 (SUMO1))
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别名
- SUMO1
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背景
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Protein Background: SUMO1 (Small ubiquitin-related modifier 1) is a ubiquitin-like protein that can be covalently attached to proteins as a monomer or a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by E3 ligases such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Involved for instance in targeting RANGAP1 to the nuclear pore complex protein RANBP2. Covalently attached to the voltage-gated potassium channel KCNB1, this modulates the gating characteristics of KCNB1.
Short Description: Recombinant SUMO1 protein - biotinylated that includes full length of human SUMO1 protein (accession number NP_001005781.1) was expressed in E. coli and contains an N-terminal His & Avi tag with a molecular weight of 15.81 kDa. This protein has been modified by biotin in vivo. The purity of the protein is ≥ 95 % by SDS-PAGE.
Aliases: Small ubiquitin-related modifier 1, SMT3H3, SMT3C, GMP1, SUMO-1, UBL1, DAP1, Sentin
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途径
- M Phase, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, Ubiquitin Proteasome Pathway
抗原
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