PRDM16 蛋白
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北京 101111
Quick Overview for PRDM16 蛋白 (ABIN7939441)
抗原
See all PRDM16 蛋白蛋白类型
宿主
资源
应用范围
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原理
- Recombinant PRDM16 protein
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!探索我们的预定义定制蛋白和定制蛋白服务！Product表达系统ConjugateOrigin价格从表达系统 Cell-free protein synthesis (CFPS)Conjugate Strep TagOrigin Human价格从 145,985.55 ¥您的项目需要进一步定制吗？联系我们，了解我们的定制蛋白解决方案
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PR Domain Containing 16 (PRDM16) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)
PRDM16 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
PR Domain Containing 16 (PRDM16) (AA 19-471) protein (His-SUMO Tag)PRDM16 宿主: Saccharomyces cerevisiae 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
PR Domain Containing 16 (PRDM16) (AA 19-471) protein (His tag)PRDM16 宿主: Saccharomyces cerevisiae 宿主: 酵母菌 Recombinant > 90 % SDS
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Recombinant PRDM16 protein is supplied in 25 mM HEPES pH 7.5, 300 mM NaCl, 20 % glycerol, 0.04 % Triton X-100, 0.5 mM TCEP.
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注意事项
- Avoid repeated freeze/thaw cycles,keep on ice when not in storage
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储存条件
- -80 °C
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储存方法
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
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- PRDM16 (PR Domain Containing 16 (PRDM16))
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别名
- PRDM16
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背景
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Protein Background: PRDM16 (Histone-lysine N-methyltransferase PRDM16), also known as CMD1LL, KMT8F, LVNC8, MEL1 and PFM13. PRDM16 was found in t(1,3)(p36,q21)-positive AML, which has similar clinicopathological features to3q21q26 syndrome, as a transcriptionally activated gene near the chromosomal breakpoint. The structure of the PRDM16 gene product is very similar to that of MDS1/EVI1. Both products have the PRdomain at the amino-terminus, 2 separated DNA binding domains with 7 and 3 tandem zinc finger repeats, CtBP-binding motifs, and other possible transcriptional regulatory domains. By similarity, PRDM16 probably catalyzes the monomethylation of free histone H3 in the cytoplasm which is then transported to the nucleus and incorporated into nucleosomes where SUV39H methyltransferases use it as a substrate to catalyze histone H3 'Lys-9' trimethylation.
Short Description: Recombinant PRDM16 protein was expressed in a baculovirus expression system as the full length protein (accession number NP_071397.3) with an N-terminal FLAG tag. The molecular weight of the protein is 141.5 kDa.
Aliases: Transcription Factor MEL1, KMT8F, Histone-Lysine N-methyltransferase PRDM16, CMD1LL, KMT8F, LVNC8, MEL1, PFM13
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途径
- Stem Cell Maintenance, Brown Fat Cell Differentiation
抗原
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