PHKG2 蛋白
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Quick Overview for PHKG2 蛋白 (ABIN7939420)
抗原
See all PHKG2 蛋白蛋白类型
宿主
资源
应用范围
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原理
- Recombinant PHKG2 protein
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!探索我们的预定义定制蛋白和定制蛋白服务!Product表达系统ConjugateOrigin价格从表达系统 HEK-293 CellsConjugate His tagOrigin Human价格从 106,314.67 ¥表达系统 Cell-free protein synthesis (CFPS)Conjugate Strep TagOrigin Human价格从 152,621.24 ¥您的项目需要进一步定制吗?联系我们,了解我们的定制蛋白解决方案
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Recombinant PHKG2 protein is supplied in 25 mM HEPES-NaOH pH 7.5, 300 mM NaCl, 10 % glycerol, 0.04 % Triton X-100, 0.5 mM TCEP.
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注意事项
- Avoid repeated freeze/thaw cycles,keep on ice when not in storage
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储存条件
- -80 °C
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储存方法
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
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- PHKG2 (phosphorylase Kinase, gamma 2 (Testis) (PHKG2))
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别名
- PHKG2
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背景
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Protein Background: Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, encoded by two different genes. The beta subunit is the same in both the muscle and hepatic isoforms, and encoded by one gene. The gamma subunit also includes the skeletal muscle and hepatic isoforms, and the hepatic isoform is encoded by this gene. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9C, also known asautosomal liver glycogenosis. PHKG2 (Phosphorylase Kinase Catalytic Subunit Gamma 2) mediates the neural and hormonal regulation of glycogen breakdown (glycogenolysis) by phosphorylating and thereby activating glycogen phosphorylase. May regulate glycogeneolysis in the testis. Diseases associated with PHKG2 include Glycogen Storage Disease Ixc and Glycogen Storage Disease Due To Liver Phosphorylase Kinase Deficiency.
Short Description: Recombinant PHKG2 protein was expressed in baculovirus expression system as the full length protein (accession number NP_000285.1) with a N-terminal FLAG tag. The molecular weight of the protein is 47.7 kDa.
Aliases: Phosphorylase Kinase Catalytic Subunit Gamma 2
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途径
- Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process
抗原
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