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PHKG2 蛋白

This Recombinant PHKG2 protein is expressed in Baculovirus infected Insect Cells.
产品编号 ABIN7939420
发货至: 中国
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Quick Overview for PHKG2 蛋白 (ABIN7939420)

抗原

See all PHKG2 蛋白
PHKG2 (phosphorylase Kinase, gamma 2 (Testis) (PHKG2))

蛋白类型

Recombinant

宿主

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资源

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Baculovirus infected Insect Cells

应用范围

Functional Studies (Func), Activity Assay (AcA), Screening Assay (ScA)
  • 原理

    Recombinant PHKG2 protein
  • 想要此Protein的其他选项吗?

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    Product
    表达系统
    Conjugate
    Origin
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    表达系统 HEK-293 Cells
    Conjugate His tag
    Origin Human
    价格从 106,314.67 ¥
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  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Recombinant PHKG2 protein is supplied in 25 mM HEPES-NaOH pH 7.5, 300 mM NaCl, 10 % glycerol, 0.04 % Triton X-100, 0.5 mM TCEP.

    注意事项

    Avoid repeated freeze/thaw cycles,keep on ice when not in storage

    储存条件

    -80 °C

    储存方法

    Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
  • 抗原

    PHKG2 (phosphorylase Kinase, gamma 2 (Testis) (PHKG2))

    别名

    PHKG2

    背景

    Protein Background: Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, encoded by two different genes. The beta subunit is the same in both the muscle and hepatic isoforms, and encoded by one gene. The gamma subunit also includes the skeletal muscle and hepatic isoforms, and the hepatic isoform is encoded by this gene. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9C, also known asautosomal liver glycogenosis. PHKG2 (Phosphorylase Kinase Catalytic Subunit Gamma 2) mediates the neural and hormonal regulation of glycogen breakdown (glycogenolysis) by phosphorylating and thereby activating glycogen phosphorylase. May regulate glycogeneolysis in the testis. Diseases associated with PHKG2 include Glycogen Storage Disease Ixc and Glycogen Storage Disease Due To Liver Phosphorylase Kinase Deficiency.

    Short Description: Recombinant PHKG2 protein was expressed in baculovirus expression system as the full length protein (accession number NP_000285.1) with a N-terminal FLAG tag. The molecular weight of the protein is 47.7 kDa.

    Aliases: Phosphorylase Kinase Catalytic Subunit Gamma 2

    途径

    Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process
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