MYST3 Protein (AA 488-778)
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北京 101111
Quick Overview for MYST3 Protein (AA 488-778) (ABIN7939357)
抗原
蛋白类型
宿主
资源
应用范围
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产品特性
- AA 488-778
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原理
- Recombinant KAT6A / MOZ (488-778) protein
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产品特性
- KAT6A (Lysine Acetyltransferase 6A), also called as MOZ, MYST3 or ZNF220, is a histone acetyltransferase that acetylates lysine residues in histone H3 and histone H4 (in vitro). It is a component of the MOZ / MORF complex which has a histone H3 acetyltransferase activity. KAT6A may act as a transcriptional coactivator for RUNX1 and RUNX2. It also acetylates p53 / TP53 at 'Lys-120' and 'Lys-382' and controls its transcriptional activity via association with PML. This protein is composed of a nuclear localization domain, a double C2H2 zinc finger domain that binds to acetylated histone tails, a histone acetyl-transferase domain, a glutamate/aspartate-rich region, and a serine- and methionine-rich transactivation domain.
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MYST Histone Acetyltransferase (Monocytic Leukemia) 3 (MYST3) (AA 81-179) protein (GST tag)
MYST3 宿主: 人 宿主: 小麦胚 Recombinant AP, AA, ELISA, WB
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Recombinant KAT6A / MOZ (488-778) protein is supplied in 25 mM HEPES-NaOH pH 7.5, 300 mM NaCl, 20 % glycerol, 0.04 % Triton X-100, and 0.5 mM TCEP.
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注意事项
- Avoid repeated freeze/thaw cycles,keep on ice when not in storage
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储存条件
- -80 °C
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储存方法
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
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- MYST3 (MYST Histone Acetyltransferase (Monocytic Leukemia) 3 (MYST3))
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别名
- KAT6A & MOZ
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背景
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Protein Background: KAT6A (Lysine Acetyltransferase 6A), also called as MOZ, MYST3 or ZNF220, is a histone acetyltransferase that acetylates lysine residues in histone H3 and histone H4 (in vitro). It is a component of the MOZ / MORF complex which has a histone H3 acetyltransferase activity. KAT6A may act as a transcriptional coactivator for RUNX1 and RUNX2. It also acetylates p53 / TP53 at 'Lys-120' and 'Lys-382' and controls its transcriptional activity via association with PML. This protein is composed of a nuclear localization domain, a double C2H2 zinc finger domain that binds to acetylated histone tails, a histone acetyl-transferase domain, a glutamate/aspartate-rich region, and a serine- and methionine-rich transactivation domain.
Short Description: Recombinant KAT6A / MOZ (488-778) protein that includes amino acids 488-778 of human KAT6A protein (accession number NP_006757.2) was expressed in a baculovirus expression system and contains an N-terminal FLAG tag. The molecular weight of the protein is 35.5 kDa. This product is the catalytic domain of KAT6A protein.
Aliases: KAT6A, MYST3
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途径
- Stem Cell Maintenance, Embryonic Body Morphogenesis
抗原
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