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MBP 蛋白

This Recombinant MBP protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN7939351
发货至: 中国
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Quick Overview for MBP 蛋白 (ABIN7939351)

抗原

See all MBP 蛋白
MBP (Myelin Basic Protein (MBP))

蛋白类型

Recombinant

宿主

  • 14
  • 4
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资源

  • 15
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大肠杆菌(E. Coli)

应用范围

Activity Assay (AcA), Functional Studies (Func), Screening Assay (ScA)
  • 原理

    Recombinant Myelin Basic Protein
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  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Recombinant Myelin Basic protein is supplied in 25 mM Tris 8.0, 300 mM NaCl, 20 % glycerol, 0.5 mM TCEP.

    注意事项

    Avoid repeated freeze/thaw cycles,keep on ice when not in storage

    储存条件

    -80 °C

    储存方法

    Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
  • 抗原

    MBP (Myelin Basic Protein (MBP))

    别名

    Myelin Basic

    背景

    Protein Background: The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined with optional post-translational modifications give a wide spectrum of isomers, with each of them potentially having a specialized function. Induces T-cell proliferation.

    Short Description: Recombinant Myelin Basic protein that includes full length of human MBP protein (accession number NP_001020252.1 ) was expressed in E. coli and contains an N-terminal His tag with a molecular weight of 23.79 kDa. The purity of the protein is ≥ 90 % by SDS-PAGE.

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