MBP 蛋白
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北京 101111
Quick Overview for MBP 蛋白 (ABIN7939351)
抗原
See all MBP 蛋白蛋白类型
宿主
资源
应用范围
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原理
- Recombinant Myelin Basic Protein
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Recombinant Myelin Basic protein is supplied in 25 mM Tris 8.0, 300 mM NaCl, 20 % glycerol, 0.5 mM TCEP.
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注意事项
- Avoid repeated freeze/thaw cycles,keep on ice when not in storage
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储存条件
- -80 °C
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储存方法
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
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- MBP (Myelin Basic Protein (MBP))
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别名
- Myelin Basic
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背景
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Protein Background: The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined with optional post-translational modifications give a wide spectrum of isomers, with each of them potentially having a specialized function. Induces T-cell proliferation.
Short Description: Recombinant Myelin Basic protein that includes full length of human MBP protein (accession number NP_001020252.1 ) was expressed in E. coli and contains an N-terminal His tag with a molecular weight of 23.79 kDa. The purity of the protein is ≥ 90 % by SDS-PAGE.
抗原
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